Type III hypersensitivity, in the Gell and Coombs classification of allergic reactions, occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes. There are three steps that lead to this response.[1] The first step is immune complex formation, which involves the binding of antigens to antibodies to form mobile immune complexes. The second step is immune complex deposition, during which the complexes leave the plasma and are deposited into tissues. Finally, the third step is the inflammatory reaction, during which the classical pathway is activated and macrophages and neutrophils are recruited to the affected tissues. Such reactions may progress to immune complex diseases.
^Usman, Norina; Annamaraju, Pavan (2021), "Type III Hypersensitivity Reaction", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 32644548, retrieved 2021-11-26
and 25 Related for: Type III hypersensitivity information
practice. Type I hypersensitivityType II hypersensitivityType IV hypersensitivity Usman, Norina; Annamaraju, Pavan (2021), "TypeIIIHypersensitivity Reaction"...
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse...
limited utility in clinical practice. Type I hypersensitivityTypeIIIhypersensitivityType IV hypersensitivity "Immunopathology". Warrington, Richard;...
Type I hypersensitivity (or immediate hypersensitivity), in the Gell and Coombs classification of allergic reactions, is an allergic reaction provoked...
caused by an exaggerated immune response (hypersensitivity). TypeIIIhypersensitivity and type IV hypersensitivity can both occur depending on the cause...
common in the immune-mediated vasculitides which are a result of typeIIIhypersensitivity. When stained with hematoxylin and eosin, they appear brightly...
Subacute bacterial endocarditis can be considered a form of type III hypersensitivity. Among the signs of subacute bacterial endocarditis are: Malaise Weakness...
fever, and lymphadenopathy. It is a type of hypersensitivity, specifically immune complex hypersensitivity (typeIII). The term serum sickness–like reaction...
is the third form of hypersensitivity in the Gell-Coombs classification, called typeIIIhypersensitivity. Such hypersensitivity progressing to disease...
School of Medicine lecture notes, Immunology, Hypersensitivity reactions. General discussion of hypersensitivity, not specific to SLE". Pathmicro.med.sc.edu...
release pro-allergic mediators (e.g. histamine); b) Type I, Type II, and TypeIIIhypersensitivity reactions of the adaptive immune system mediated by...
throat or a streptococcal skin infection. It is classified as a typeIIIhypersensitivity reaction. Symptoms of PSGN develop within 10 days following a...
sickness-like reaction in some individuals. Serum sickness is a typeIIIhypersensitivity reaction that occurs one to three weeks after exposure to drugs...
Arthus may refer to: Arthus reaction, a type of local typeIIIhypersensitivity reaction Arthus-Bertrand, a French maker of medals and decorations Tangara...
termed hypersensitivity to mosquito bites, are excessive reactions of varying severity to mosquito bites. They are allergic hypersensitivity reactions...
dome" pattern. Tubules also display the symptoms of a typical TypeIIIhypersensitivity reaction, which causes the endothelial cells to proliferate, which...
conjugate with a carrier, could induce contact hypersensitivity, which is a type IV delayed hypersensitivity reaction mediated by T cells and dendritic cells...
or an absolute increase in glomerular filtration rate (GFR). Most young Type 1 diabetic patients experience glomerular hyperfiltration, a typical functional...
disorder is consistent with an immune-complex-mediated mechanism, a typeIIIhypersensitivity reaction. This disorder produces proteins that have different...
tissues trigger TypeIIIhypersensitivity reactions. Type IV hypersensitivity (also known as cell-mediated or delayed typehypersensitivity) usually takes...