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Transcellular transport information


Transcellular transport involves the transportation of solutes by a cell through a cell.[1] Transcellular transport can occur in three different ways active transport, passive transport, and transcytosis.

  1. ^ Rhoades, Rodney A.; Bell, David R. (2012). "Plasma membrane. membrane transport, and resting membrane potential". Medical physiology : principles for clinical medicine (4th ed., International ed.). Philadelphia, Pa.: Lippincott Williams & Wilkins. p. 36. ISBN 978-1451110395.

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Transcellular transport

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Transcellular transport involves the transportation of solutes by a cell through a cell. Transcellular transport can occur in three different ways active...

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Paracellular transport

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the intercellular space between the cells. It is in contrast to transcellular transport, where the substances travel through the cell, passing through...

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Epithelium

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filtration, secretion, selective absorption, germination, and transcellular transport. Compound epithelium has protective functions. Epithelial layers...

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Capillary

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than 3 nm such as albumin and other large proteins pass through transcellular transport carried inside vesicles, a process which requires them to go through...

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Immunoglobulin A

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poly-Ig receptor (130 kD) that is responsible for the uptake and transcellular transport of oligomeric (but not monomeric) IgA across the epithelial cells...

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Transcytosis

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(also known as cytopempsis) is a type of transcellular transport in which various macromolecules are transported across the interior of a cell. Macromolecules...

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Vascular permeability

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"Regulation of Endothelial Permeability via Paracellular and Transcellular Transport Pathways". Annual Review of Physiology. 72 (1): 463–493. doi:10...

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Proximal tubule

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in the proximal tubule through active transport, solvent drag, and paracellular electrodiffusion. Active transport is mainly through the sodium/hydrogen...

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Tight junction

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the basolateral surface) to be preserved. This allows polarized transcellular transport and specialized functions of apical and basolateral membranes....

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Small molecule

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insufficient condition for oral bioavailability as it allows for transcellular transport through intestinal epithelial cells. In addition to intestinal...

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Extracellular fluid

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cations and anions between the two fluid compartments. Transcellular fluid is formed from the transport activities of cells, and is the smallest component...

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Partition coefficient

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in the intestinal epithelium (a process known as transcellular transport). For efficient transport, the drug must be hydrophobic enough to partition...

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Cimetidine

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Kimura N, Okuda M, Masuda S, Katsura T, Inui K (June 2005). "Transcellular transport of creatinine in renal tubular epithelial cell line LLC-PK1". Drug...

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TRPV6

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dietary Ca2+), the transcellular pathway is required for adequate Ca2+ absorption. Three important steps in transcellular Ca2+ transport are recognized:...

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Buccal administration

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mechanism of passive diffusion, and hydrophobic drugs are transported through the transcellular pathway. This route of administration is beneficial for...

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ArsB and ArsAB transporters

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transporter on the other side of the cell to permit the effective transcellular transport of the nutrient. ArsA proteins are homologous to nitrogenase iron...

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Cephaloridine

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secreted through the proximal tubular cells via unidirectional transcellular transport. The organic anions are taken up from the blood into the cells...

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Focused ultrasound for intracranial drug delivery

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causes cellular changes that further enhance paracellular and transcellular transport of therapeutics across the BBB. However, this mechanical stress...

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Major facilitator superfamily

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The major facilitator superfamily (MFS) is a superfamily of membrane transport proteins that facilitate movement of small solutes across cell membranes...

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Solvent drag

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the paracellular, rather than transcellular, pathway between the tubular cells. It is seen e.g. in the passive transport in renal sodium reabsorption,...

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Polymeric immunoglobulin receptor

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Kraehenbuhl JP, Blobel G (December 1980). "Receptor-mediated transcellular transport of immunoglobulin: synthesis of secretory component as multiple...

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Renal sodium reabsorption

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to diffuse passively either the transcellular or paracellular way. In the distal convoluted tubule sodium is transported against an electrochemical gradient...

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Cholangiocyte

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of bile acids via ATP-driven transporters. This results in passive transcellular and paracellular secretion of fluid and electrolytes through an osmotic...

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Intestinal permeability

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mediated via two major routes: Transepithelial or transcellular permeability. This consists of specific transport of solutes across the epithelial cells. It...

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Intestinal epithelium

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through two major routes: the transcellular (transepithelial) route and the paracellular route. This consists of specific transport of solutes across the epithelial...

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Gitelman syndrome

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distal convoluted tubule itself are altered as well. For instance, transcellular calcium reabsorption is increased. This has been suggested to be the...

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Aquaporin

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transcellular pathways. Specifically, aquaporins are found in the vacuolar membrane, in addition to the plasma membrane of plants; the transcellular pathway...

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