Tolmetin information

Tolmetin
Clinical data
Trade names	Tolectin
AHFS/Drugs.com	Monograph
MedlinePlus	a681033
Routes of; administration	By mouth
ATC code	M01AB03 (WHO) M02AA21 (WHO);
Legal status
Legal status	AU: S4 (Prescription only);
Pharmacokinetic data
Elimination half-life	1-2 hours, next phase up to 5 hours
Identifiers
	IUPAC name [1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid;
CAS Number	26171-23-3 ;
PubChem CID	5509;
IUPHAR/BPS	7311;
DrugBank	DB00500 ;
ChemSpider	5308 ;
UNII	D8K2JPN18B;
KEGG	D02355 ;
ChEBI	CHEBI:71941 ;
ChEMBL	ChEMBL1020 ;
CompTox Dashboard (EPA)	DTXSID2043951 ;
ECHA InfoCard	100.043.164
Chemical and physical data
Formula	C15H15NO3
Molar mass	257.289 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1ccc(n1C)CC(=O)O)c2ccc(cc2)C;
	InChI InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18) ; Key:UPSPUYADGBWSHF-UHFFFAOYSA-N ;
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Tolmetin (/ˈtɒlmətɪn/) is a nonsteroidal anti-inflammatory drug (NSAID) of the heterocyclic acetic acid derivative class.

Tolmetin was originally approved by the US FDA in 1976. It is available internationally.^[1]

It is used primarily to reduce hormones that cause pain, swelling, tenderness, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis, including juvenile rheumatoid arthritis. In the United States it was marketed as Tolectin and comes as a tablet or capsule.

^ "Tolmetin: MedlinePlus Drug Information". medlineplus.gov. Retrieved 2023-10-27.

[1] "Tolmetin: MedlinePlus Drug Information". medlineplus.gov. Retrieved 2023-10-27.

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