304nm (trans-resveratrol, in water) 286nm (cis-resveratrol, in water)[1]
Hazards
GHS labelling:[5]
Pictograms
Signal word
Warning
Hazard statements
H319
Precautionary statements
P264, P280, P305+P351+P338, P337+P313
Lethal dose or concentration (LD, LC):
LD50 (median dose)
23.2 μM (5.29 g)[4]
Safety data sheet (SDS)
Fisher Scientific[2] Sigma Aldrich[3]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol or polyphenol and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi.[6][7] Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries, and peanuts.[8][9]
Although commonly used as a dietary supplement and studied in laboratory models of human diseases,[10] there is no high-quality evidence that resveratrol improves lifespan or has a substantial effect on any human disease.[11][12]
^ abCamont, Laurent; Cottart, Charles-Henry; Rhayem, Yara; et al. (February 2009). "Simple spectrophotometric assessment of the trans-/cis-resveratrol ratio in aqueous solutions". Anal. Chim. Acta. 634 (1): 121–128. Bibcode:2009AcAC..634..121C. doi:10.1016/j.aca.2008.12.003. PMID 19154820.
^ ab"Resveratrol MSDS on Fisher Scientific website". Archived from the original on 2012-11-03. Retrieved 2012-03-06.
^Resveratrol MSDS on www.sigmaaldrich.com
^Bechmann LP, Zahn D, Gieseler RK, et al. (June 2009). "Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells". Hepatology Research. 39 (6): 601–608. doi:10.1111/j.1872-034X.2008.00485.x. PMC 2893585. PMID 19207580.
^GHS: Sigma-Aldrich R5010
^"Resveratrol". Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR. 11 June 2015. Retrieved 26 August 2019.
^Fremont, Lucie (January 2000). "Biological Effects of Resveratrol". Life Sciences. 66 (8): 663–673. doi:10.1016/S0024-3205(99)00410-5. PMID 10680575.
^Jasiński M, Jasińska L, Ogrodowczyk M (August 2013). "Resveratrol in prostate diseases – a short review". Central European Journal of Urology. 66 (2): 144–149. doi:10.5173/ceju.2013.02.art8. PMC 3936154. PMID 24579014.
^Cite error: The named reference pe was invoked but never defined (see the help page).
^"Resveratrol". MedlinePlus. 1 April 2019. Retrieved 22 September 2019.
^Cite error: The named reference pmid21698226 was invoked but never defined (see the help page).
^Sahebkar A, Serban C, Ursoniu S, et al. (2015). "Lack of efficacy of resveratrol on C-reactive protein and selected cardiovascular risk factors – Results from a systematic review and meta-analysis of randomized controlled trials". International Journal of Cardiology. 189: 47–55. doi:10.1016/j.ijcard.2015.04.008. PMID 25885871.
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol or polyphenol and a phytoalexin produced by several plants in...
5-dimethoxy-4-hydroxystilbene) is a stilbenoid chemically related to resveratrol. In plants, it serves a defensive phytoalexin role. Pterostilbene is...
grapes contained high concentrations of resveratrol, but subsequent studies have found no or little resveratrol in muscadine grapes. Other muscadine polyphenols...
average of 1.9 (±1.7) mg of trans-resveratrol per liter. For comparison, dietary supplements of resveratrol (trans-resveratrol content varies) may contain as...
synthesis of the stilbenoid resveratrol, a natural compound found in common foods like grapes, wines and nuts. Resveratrol is a biologically important...
Piceid is a stilbenoid glucoside and is a major resveratrol derivative in grape juices. It can be found in the bark of Picea sitchensis. It can also be...
in oleanolic and ursolic acid. Cis-epsilon-viniferin, trans-resveratrol, trans-resveratrol-4'-O-beta-D-glucopyranoside, trans-epsilon-viniferin, gnetin...
Ampelopsin B, a resveratrol oligomer Cyphostemmin A, a resveratrol dimer Cyphostemmin B, a resveratrol dimer Delta-viniferin, a resveratrol dimer Epsilon-viniferin...
reaction is in the laboratory synthesis of the phytoestrogenic stilbene resveratrol (c.f. fo-ti). Erlenmeyer–Plöchl azlactone and amino-acid synthesis Stobbe...
pine and vaccinium berries Resveratrol in grapes Glycosides Astringin in the bark of Norway spruce Piceid is a resveratrol derivative in grape juices...
focused on resveratrol formulations and derivatives as activators of the SIRT1 enzyme; Sinclair became known for making statements about resveratrol like:...
conditions. Resveratrol has been shown to increase the mean (56%) and maximum life span (59%) of Nothobranchius furzeri, but resveratrol has not been...
team of researchers, leading to the development of two further patents, Resveratrol and Viniferine. In September 1999, Mathilde and Bertrand Thomas created...
discovered that melinjo strobili are rich in a stilbenoid composed of resveratrol and identified as a dimer. This result was published in XXIII International...
the basis of their basic skeleton. An example of a plant phenol is: Resveratrol, a C14 stilbenoid produced by e.g. grapes. Alkaloids are a diverse group...
more effective for some applications than L-carnitine. Acetylation of resveratrol holds promise as one of the first anti-radiation medicines for human...
Pinostilbene is a stilbenoid found in Gnetum venosum and in the bark of Pinus sibirica. Oligostilbenoids from Gnetum venosum. Boralle N, Gottlieb H.E,...
activation. However, resveratrol was later shown to directly activate Sirtuin 1 against non-modified peptide substrates. Resveratrol also enhances the binding...
branches into growing polymers.[citation needed] The trans isomer of resveratrol can be converted to the cis isomer in a photochemical reaction. Thermal...
effective CRM have been identified to date. Candidate compounds include: Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural...
kobophenol A, a substance that is formed by combining four molecules of resveratrol. In biochemistry, it similarly refers to a biomolecule formed of four...
fiber in amounts similar to several tree nuts. Peanut skins contain resveratrol, which is under preliminary research for its potential effects on humans...
4-coumaroyl-CoA, whereas its 3 products are CoA, 3,4',5-trihydroxy-stilbene (resveratrol), and CO2. This enzyme belongs to the family of transferases, To be specific...
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