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Curcumin information


Curcumin
Skeletal formula
Enol form
Skeletal formula
Keto form
Ball-and-stick model
Ball-and-stick model
Names
Pronunciation /ˈkɜːrkjʊmɪn/
Preferred IUPAC name
(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
Other names
  • (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
  • Diferuloylmethane
  • Curcumin I
  • C.I. 75300
  • Natural Yellow 3
Identifiers
CAS Number
  • 458-37-7 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:3962 checkY
ChEMBL
  • ChEMBL116438 ☒N
ChemSpider
  • 839564 checkY
ECHA InfoCard 100.006.619 Edit this at Wikidata
E number E100 (colours)
IUPHAR/BPS
  • 7000
KEGG
  • C10443
PubChem CID
  • 969516
UNII
  • IT942ZTH98 checkY
CompTox Dashboard (EPA)
  • DTXSID8031077 Edit this at Wikidata
InChI
  • InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ checkY
    Key: VFLDPWHFBUODDF-FCXRPNKRSA-N checkY
  • InChI=1/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
    Key: VFLDPWHFBUODDF-FCXRPNKRBF
SMILES
  • O=C(\C=C\c1ccc(O)c(OC)c1)CC(=O)\C=C\c2cc(OC)c(O)cc2
Properties
Chemical formula
C21H20O6
Molar mass 368.385 g·mol−1
Appearance Bright yellow-orange powder
Melting point 183 °C (361 °F; 456 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Curcumin is a bright yellow chemical produced by plants of the Curcuma longa species. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family, Zingiberaceae. It is sold as a herbal supplement, cosmetics ingredient, food flavoring, and food coloring.[1]

Chemically, curcumin is a polyphenol, more particularly a diarylheptanoid, belonging to the group of curcuminoids, which are phenolic pigments responsible for the yellow color of turmeric.[2]

Laboratory and clinical research have not confirmed any medical use for curcumin. It is difficult to study because it is both unstable and poorly bioavailable. It is unlikely to produce useful leads for drug development as a lead compound.[3]

  1. ^ Majeed S (28 December 2015). "The State of the Curcumin Market". Natural Products Insider. Archived from the original on October 17, 2017. Retrieved February 29, 2016.
  2. ^ CID 969516 from PubChem
  3. ^ Cite error: The named reference nelson was invoked but never defined (see the help page).

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Curcumin

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Curcumin is a bright yellow chemical produced by plants of the Curcuma longa species. It is the principal curcuminoid of turmeric (Curcuma longa), a member...

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Turmeric

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turmeric constituent, curcumin. Turmeric powder has a warm, bitter, black pepper-like flavor and earthy, mustard-like aroma. Curcumin, a bright yellow chemical...

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Rosocyanine

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which are formed by the reaction between curcumin and borates. The color reaction between borates and curcumin is used for the spectrophotometric determination...

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Curcuminoid

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a relatively small class of plant secondary metabolites that includes curcumin, demethoxycurcumin, and bisdemethoxycurcumin, all isolated from turmeric...

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Curcumin synthase

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Curcumin synthase categorizes three enzyme isoforms (CURS1, 2, and 3), type III polyketide synthases (PKSs) present in the leaves and rhizome of the turmeric...

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Boron

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materials, the colorimetric curcumin method is used. Boron is converted to boric acid or borates and on reaction with curcumin in acidic solution, a red...

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Desmethoxycurcumin

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grade curcumin contains a mixture of curcuminoids (desmethoxycurcumin 10–20%, bisdesmethoxycurcumin 5% or less). Bis-desmethoxycurcumin Curcumin Sotanaphun...

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Fraise Tagada

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flavoring, curcumin (coloring), carmine, and mixed carotenes. There have, however, also been versions produced that do not contain curcumin. "Pourquoi...

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Bisdemethoxycurcumin

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Bisdemethoxycurcumin is a curcuminoid found (along with the curcuminoids curcumin and demethoxycurcumin) in turmeric (Curcuma longa), but absent in Javanese...

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Reagent

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class them instead as pan-assay interference compounds. One example is curcumin. Limiting reagent Common reagents Product Reagent bottle Substrate All...

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Neurofibrillary tangle

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treatment. Curcumin (as Longvida) has been shown to reduce memory deficit and tau monomers in animal models, however no clinical trials have shown curcumin to...

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Erode Turmeric

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the Government of India in 2019. Erode turmeric is known for its high curcumin (>90%). Among the two major varieties of turmeric, the Chinna Nadan variety...

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Phytosome

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Ginkgo biloba, silybin isolated from milk thistle (Silybum marianum), curcumin isolated from turmeric, and green tea extract (Camellia sinensis). An attempt...

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Bharat Aggarwal

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cancer, and the anti-cancer effects of spices and herbs, particularly curcumin (a chemical constituent of the spice turmeric). He was a professor in the...

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Dimethylcurcumin

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AdisInsight. Shi Q, Shih CC, Lee KH (2009). "Novel anti-prostate cancer curcumin analogues that enhance androgen receptor degradation activity". Anticancer...

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Sonodynamic therapy

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viability. Interestingly, curcumin is a spice that also can act as a sensitizer for PDT and SDT. In a study by Waksman et al., curcumin was able to impact macrophages...

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Additive effect

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additive effects with independent actions. For example, artemisinin and curcumin both exert antimalarial effects. Artemisinin works by being metabolized...

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Japanese encephalitis

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encephalitis. Curcumin has been shown to impart neuroprotection against Japanese encephalitis infection in an in vitro study. Curcumin possibly acts by...

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Azerizin

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blend of the natural ingredients nicotinamide, azelaic acid, quercetin and curcumin that purportedly combine the anti-inflammatory and antimicrobial properties...

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Salicylic acid

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Rofecoxib Tilmacoxib Valdecoxib; Others/unsorted: Anitrazafen Clobuzarit Curcumin DuP-697 FK-3311 Flumizole FR-122047 Glimepiride Hyperforin Itazigrel L-655240...

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Glossary of chemical formulae

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C21H18FN5O5S Avutometinib C21H19ClN4O2 Setanaxib 1218942-37-0 C21H20O6 curcumin C21H22N2O4 Picralinal C21H22O4 Taxamairin A 110300-76-0 C21H23FN2O4 Z-FA-FMK...

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Mentha

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(dibenzoxazepine; DBO) CS gas (2-chlorobenzal malononitrile) Cuminaldehyde (cumin) Curcumin (turmeric) Dehydroligustilide (celery) Diallyl disulfide Dicentrine (Lindera...

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Nicotinamide

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mercaptan Apicidin Belinostat Butyric acid (butyrate) Capsaicin Citarinostat Curcumin Diallyl disulfide Entinostat Fimepinostat Givinostat Indole-3-carbinol...

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E100

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Panzerkampfwagen E-100, a proposed German World War II super-heavy tank Curcumin, food coloring from turmeric designated by E number E100 Neat ethanol fuel...

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Mast cell activation syndrome

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Antileukotrienes, such as montelukast or zileuton as well as natural products (e.g., curcumin or St. John's wort extracts) Nonsteroidal anti-inflammatory drugs, including...

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Horseradish

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(dibenzoxazepine; DBO) CS gas (2-chlorobenzal malononitrile) Cuminaldehyde (cumin) Curcumin (turmeric) Dehydroligustilide (celery) Diallyl disulfide Dicentrine (Lindera...

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Tobacco

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(dibenzoxazepine; DBO) CS gas (2-chlorobenzal malononitrile) Cuminaldehyde (cumin) Curcumin (turmeric) Dehydroligustilide (celery) Diallyl disulfide Dicentrine (Lindera...

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Rubrocurcumin

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red-colored dye that is formed by the reaction of curcumin and boric acid. The reaction of curcumin with borates in presence of oxalic acid produces rubrocurcumin...

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