Tetrahydrocorticosterone information

Tetrahydrocorticosterone
Names
	IUPAC name 3α,11β,21-Trihydroxy-5β-pregnan-20-one
	Systematic IUPAC name 1-[(1S,3aS,3bS,5aR,7R,9aS,9bS,10S,11aS)-7,10-Dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-hydroxyethan-1-one
	Other names 3α,5α-Tetrahydrocorticosterone; 5β-Pregnane-3α,11β,21-triol-20-one
Identifiers
CAS Number	68-42-8 ;
3D model (JSmol)	Interactive image;
ChemSpider	17215927;
ECHA InfoCard	100.000.627
PubChem CID	65553;
UNII	PUW84K2LEC ;
CompTox Dashboard (EPA)	DTXSID901015843 ;
	InChI InChI=1S/C21H34O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-17,19,22-24H,3-11H2,1-2H3/t12-,13-,14+,15+,16-,17+,19-,20+,21+/m1/s1 Key: RHQQHZQUAMFINJ-DTDWNVJFSA-N;
	SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CC[C@@H]4C[C@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)CO;
Properties
Chemical formula	C21H34O4
Molar mass	350.499 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

3α,5α-Tetrahydrocorticosterone (3α,5α-THB), or simply tetrahydrocorticosterone (THB or THCC), is an endogenous glucocorticoid hormone.^[1]

^ McInnes KJ, Kenyon CJ, Chapman KE, et al. (May 2004). "5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor". The Journal of Biological Chemistry. 279 (22): 22908–12. doi:10.1074/jbc.M402822200. PMID 15044432.

[pmid15044432-1] McInnes KJ, Kenyon CJ, Chapman KE, et al. (May 2004). "5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor". The Journal of Biological Chemistry. 279 (22): 22908–12. doi:10.1074/jbc.M402822200. PMID 15044432.

Tetrahydrocorticosterone information

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Tetrahydrocorticosterone

THB

C21H34O4

Dihydrotestosterone

Cortisol

Glucocorticoid

Steroid

Clobetasol

Corticosteroid

Betamethasone valerate

Progesterone

Triamcinolone

Dexamethasone

Triamcinolone acetonide

Estrogen

Fluticasone propionate

Prednisolone

Clobetasol propionate

Ketoconazole

Methylprednisolone acetate

Methylprednisolone

Methylprednisolone aceponate

Mometasone

Cortisone

Prednisolone acetate

Hydrocortisone acetate

Fluocinonide

Dehydroepiandrosterone

Estradiol

Hydrocortisone