Sulfathiazole is an organosulfur compound used as a short-acting sulfa drug.[1] Formerly, it was a common oral and topical antimicrobial, until less toxic alternatives were discovered.[2]
Sulfathiazole exists in various forms (polymorphs). The imine tautomer is dominant in solid samples.[3]
^Mertschenk B, Beck F, Bauer W (2002). "Thiourea and Thiourea Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Wiley-VCH. doi:10.1002/14356007.a26_803. ISBN 3527306730.
^Rouf A, Tanyeli C (June 2015). "Bioactive thiazole and benzothiazole derivatives". European Journal of Medicinal Chemistry. 97: 911–27. doi:10.1016/j.ejmech.2014.10.058. PMID 25455640.
^Kruger GT, Gafner G (February 1971). "The crystal structure of sulphathiazole II". Acta Crystallographica Section B. 27 (2): 326–33. Bibcode:1971AcCrB..27..326K. doi:10.1107/S0567740871002176.
Sulfathiazole is an organosulfur compound used as a short-acting sulfa drug. Formerly, it was a common oral and topical antimicrobial, until less toxic...
drug remains in the intestine and only 5% is hydrolyzed, slowly, to sulfathiazole and is absorbed. The drug is used for its antibacterial activity in...
delivers the pyrimidine. The pharmaceuticals thiobarbituric acid and sulfathiazole are prepared using thiourea. 4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole...
sitamaquin, sitaxentan, sulfamiderazin, sulfapyridine, sulfaquinoxaline, sulfathiazole, sulfazecin, thiamylal and mesna. The disodium salt of cromolyn is also...
Sulfabenzamide is an antibacterial/antimicrobial. Often used in conjunction with sulfathiazole and sulfacetamide (trade name – Sultrin) as a topical, intravaginal...
Philippines. After the war ended in 1945, Que bought ₱100-worth of Sulfathiazole pills. He sold these drugs in single doses and using his savings decided...
Winthrop Chemical producing contaminated sulfathiazole tablets contaminated with phenobarbital. Each sulfathiazole tablet was contaminated with about 350 mg...
colitis, gastroenteritis and intestinal surgery. It is a derivative of sulfathiazole in which the phthalic acid substitution on the aniline nitrogen prevents...
manufacturing existing pharmaceutical preparations. The sulfa drug Sulfathiazole was one of the results of these research activities. The company Tika...
Great Coates, next to the Europarc in the west of Grimsby; it has been there since 1951, firstly as Ciba (Chemical Industry Basel) making sulfathiazole...
clinical practice, in a 51-year-old man with acute renal failure caused by sulfathiazole poisoning. 1959 – Paul Doolan and Richard Ruben of Naval Hospital Oakland...
eruption Examples of drug eruptions. (A) Bullous dermatitis caused by sulfathiazole (B) Fixed drug eruption caused by phenolphtalein (C) Bullous erythema...
give aminothiazoles. This reaction was once used in the preparation of sulfathiazole, one of the first sulfa drugs. Chloroacetaldehyde is a building block...
initiated studies on antibiotic therapies for plague, beginning with sulfathiazole in 1939 and continuing with tetracyclines and related antibiotics during...
ceftazidime, amoxicillin/clavulanic acid, piperacillin, chloramphenicol, and sulfathiazole have been reported to be effective against the bacteria in vitro. B...
known to have different polymorphic forms. Such a case is in the drug sulfathiazole, a common oral and topical antimicrobial, which has over a hundred different...
studying sulfanilamides. Following the introduction of a new drug, sulfathiazole, which replaced sulfadiazine, Gabel synthesised this in his laboratory...
chemicals and pharmaceuticals. Initial production was antibacterial agent Sulfathiazole (branded as Cibazol). The plant became part of Ciba Chemicals in 1962...
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