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Splenectomy
Surgically removed spleen of a child with thalassemia. It is about 15 times larger than normal.
ICD-9-CM
41.43, 41.5
MeSH
D013156
OPS-301 code
5-413
[edit on Wikidata]
A splenectomy is the surgical procedure that partially or completely removes the spleen. The spleen is an important organ in regard to immunological function due to its ability to efficiently destroy encapsulated bacteria. Therefore, removal of the spleen runs the risk of overwhelming post-splenectomy infection, a medical emergency and rapidly fatal disease caused by the inability of the body's immune system to properly fight infection following splenectomy or asplenia.[1]
Common indications for splenectomy include trauma, tumors, splenomegaly or for hematological disease such as sickle cell anemia or thalassemia.[2]
^Taniguchi, Leandro Utino; Correia, Mário Diego Teles; Zampieri, Fernando Godinho (December 2014). "Overwhelming post-splenectomy infection: narrative review of the literature". Surgical Infections. 15 (6): 686–693. doi:10.1089/sur.2013.051. ISSN 1557-8674. PMID 25318011.
^Weledji, Elroy P. (2014). "Benefits and risks of splenectomy". International Journal of Surgery (London, England). 12 (2): 113–119. doi:10.1016/j.ijsu.2013.11.017. ISSN 1743-9159. PMID 24316283.
A splenectomy is the surgical procedure that partially or completely removes the spleen. The spleen is an important organ in regard to immunological function...
the abdomen. The surgical process to remove the spleen is known as a splenectomy. The spleen is underneath the left part of the diaphragm, and has a smooth...
occurs for several reasons: Following splenectomy due to splenic rupture from trauma or because of tumor After splenectomy with the goal of interfering with...
After splenectomy, 11.6 - 75 percent of ITP cases relapsed, and 8.7 - 40 percent of ITP cases had no response to splenectomy. The use of splenectomy to treat...
indicate dietary supplementation of folic acid and splenectomy, the surgical removal of the spleen. Splenectomy is indicated for moderate to severe cases, but...
errors in diagnostic imaging or continued symptoms after therapeutic splenectomy. Polysplenia is the presence of multiple accessory spleens rather than...
and beta-thalassemia Hemoglobin C Disease Iron deficiency anemia Post-splenectomy: A major function of the spleen is the clearance of opsonized, deformed...
bone marrow; and the potential for correction of these abnormalities by splenectomy. Splenomegaly is usually associated with increased workload (such as...
removal of the spleen (splenectomy) is only required if complications ensue; surgical removal predisposes to overwhelming post-splenectomy infections. Several...
removal of the tumor with the affected organ, such as with a splenectomy. Splenectomy alone gives an average survival time of 1–3 months. The addition...
Patients with thalassemia major are more inclined to have a splenectomy. The use of splenectomies have been declining in recent years due to decreased prevalence...
disease may respond to splenectomy. More importantly, a lymphoma localized to the spleen may only be found after splenectomy. Patients with cold agglutinin...
ISBN 978-1437716047. McBride JA, Dacie JV, Shapley R (February 1968). "The effect of splenectomy on the leucocyte count". British Journal of Haematology. 14 (2): 225–31...
cells. Primary treatment for patients with symptomatic HS has been total splenectomy, which eliminates the hemolytic process, allowing normal hemoglobin,...
right-sided gastropexy. Depending on the severity, partial gastrectomy and/or splenectomy may be indicated if the relevant tissues have necrosed due to ischemia...
stand for: Overwhelming post-splenectomy infection, rapidly fatal septicaemia in a patient who has undergone splenectomy (removal of the spleen). Office...
Adrienne M.; Brown, Dorothy C. (15 May 2013). "Association between previous splenectomy and gastric dilatation-volvulus in dogs: 453 cases (2004–2009)". Journal...
removed. However, the impact of a splenectomy on post-transplant regression is unknown. The COG JMML study includes splenectomy as a standard component of treatment...
embolization is a minimally invasive procedure and, where successful, avoids splenectomy. If an individual's spleen is enlarged, as is frequent in mononucleosis...
of small endocrine pancreatic tumours, partial nephrectomy, salvage splenectomy, head and neck procedures and gynecological tumours. Instruments used...
treatment, though peripheral neuropathy is a common troublesome side-effect. Splenectomy is sometimes considered as a treatment option for patients with myelofibrosis...
which he lost a significant amount of blood. He required an emergency splenectomy and remained critically ill in the hospital for many months, at times...
asplenia, can occur by autosplenectomy or the surgical counterpart, splenectomy. Asplenia can increase susceptibility to infection. Autosplenectomy can...
people with complement deficiencies and patients who have undergone splenectomy". Clinical Microbiology Reviews. 23 (4): 740–80. doi:10.1128/CMR.00048-09...
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