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Medical condition
Juvenile myelomonocytic leukemia
Specialty
Oncology, hematology
Usual onset
Under 4 years old[1]
Treatment
Stem cell transplant
Frequency
One to two children out of one million diagnosed each year[1]
Juvenile myelomonocytic leukemia (JMML) is a rare form of chronic leukemia (cancer of the blood) that affects children, commonly those aged four and younger.[2] The name JMML now encompasses all diagnoses formerly referred to as juvenile chronic myeloid leukemia (JCML), chronic myelomonocytic leukemia of infancy, and infantile monosomy 7 syndrome. The average age of patients at diagnosis is two (2) years old.[2] The World Health Organization has included JMML as a subcategory of myelodysplastic and myeloproliferative disorders.
^ ab"Juvenile Myelomonocytic Leukemia". St. Jude Children's Research Hospital. Retrieved 2003-09-24.
Juvenilemyelomonocyticleukemia (JMML) is a rare form of chronic leukemia (cancer of the blood) that affects children, commonly those aged four and younger...
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leukemia (CLL) is another form of chronic leukemia, but is extremely rare in children. Juvenilemyelomonocyticleukemia (JMML) is a form of leukemia in...
the treatment of myelodysplastic syndrome, myeloid leukemia, and juvenilemyelomonocyticleukemia. It is a chemical analog of cytidine, a nucleoside in...
most types of AML, except for acute myelomonocyticleukemia (AMML). The skin can be involved in the form of leukemia cutis; Sweet's syndrome; or non-specific...
Chronic myelomonocyticleukemia (CMML) is a type of leukemia, which are cancers of the blood-forming cells of the bone marrow. In adults, blood cells are...
Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells. It is a form of leukemia characterized by...
transplantation to consolidate the response. Treatment for juvenilemyelomonocyticleukemia can include splenectomy, chemotherapy, and bone marrow transplantation...
disease. Patients with myelofibrosis have an increased risk of acute meyloid leukemia and frank bone marrow failure. In 2016, prefibrotic primary myelofibrosis...
originally designed for the treatment of chronic myelomonocyticleukemia (CMML) and juvenilemyelomonocyticleukemia (JMML). In vitro studies on human cells have...
RAS-associated autoimmune leukoproliferative disorder (RALD) or juvenilemyelomonocyticleukemia (JMML). These syndromes may share some features with RASopathies...
in people with a mutation of KRAS and an increased risk of juvenilemyelomonocyticleukemia exists for a mutation of PTPN11. In the future, studies may...
Hepatoblastoma and hepatocellular carcinoma (liver cancer) Juvenilemyelomonocyticleukemia Overall, treating childhood cancer requires a multidisciplinary...
myelomonocytic, leukemia, NOS Type 1 Type 2 M9946/3 Juvenilemyelomonocyticleukemia M9948/3 Aggressive NK cell leukemia M9950/3 Polycythemia vera Polycythemia rubra...
myeloproliferative neoplasms similar to those found in NF1 juvenilemyelomonocyticleukemia/JMML) were used to study the effects of the specific MEK inhibitor...
transformation and leukemogenesis. GAB2 also plays a role in juvenilemyelomonocyticleukemia (JMML). Studies have shown the protein's involvement in the...
(Apr 2004). "HCMOGT-1 is a novel fusion partner to PDGFRB in juvenilemyelomonocyticleukemia with t(5;17)(q33;p11.2)". Cancer Res. 64 (8): 2649–51. doi:10...
associated with two cases of acute promyelocytic leukemia and one case of juvenilemyelomonocyticleukemia. Relatively little is known about function of...
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