Sorafenib, sold under the brand name Nexavar,[3] is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma.
^Cite error: The named reference Nexavar FDA label was invoked but never defined (see the help page).
^"Nexavar EPAR". European Medicines Agency (EMA). 17 September 2018. Archived from the original on 14 October 2021. Retrieved 18 September 2022.
^"FDA Approves Nexavar for Patients with Inoperable Liver Cancer" (Press release). FDA. 19 November 2007. Archived from the original on 2 January 2017. Retrieved 10 November 2012.
Sorafenib, sold under the brand name Nexavar, is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma)...
phase 3 randomized, open-label, clinical trial of Pexa-Vec plus sorafenib versus sorafenib is being conducted on patients with advanced hepatocellular carcinoma...
people with hepatocellular carcinoma who have been previously treated with sorafenib. The approval was based on CELESTIAL (NCT01908426), a randomized (2:1)...
months. The most common side effects of Sorafenib include a hand-foot skin reaction and diarrhea. Sorafenib is thought to work by blocking growth of...
with advanced hepatocellular carcinoma who were previously treated with sorafenib. MetastaticCRC: After the CORRECT trial, two phase 3 trials (CONSIGN,...
and various receptor tyrosine kinases. It is a deuterated derivative of sorafenib with improved pharmacokinetic properties. Keam, Susan J.; Duggan, Sean...
diastolic was reported in the first 24 hours after the first treatment with sorafenib, a VEGF pathway inhibitor.[non-primary source needed] Because these drugs...
Peginterferon alfa-2b is being studied to treat plexiform neurofibromas. Sorafenib is being studied for treatment of unresectable plexiform neurofibroma...
partner at Institutional Venture Partners (an original Onyx backer). Sorafenib, co-developed and co-marketed with Bayer and sold under the trade name...
sorafenib to transition to tivozanib following progression disease but not those on the experimental arm using tivozanib to transition to sorafenib....
showed significantly extended progression-free survival when compared to sorafenib. In December 2011, the Oncologic Drugs Advisory Committee (ODAC) voted...
of liver cancer produced sorafenib, a targeted therapy drug that prevents cell proliferation and blood cell growth. Sorafenib obtained FDA approval for...
Parkinson's disease. Examples of "promiscuous" cancer drugs include: Sutent, Sorafenib, Zactima, and AG-013736.[citation needed] In the field of drugs used to...
Assay, which is used to detect the FLT3 mutation in patients with AML. Sorafenib has been reported to show significant activity against Flt3-ITD positive...
followed by bevacizumab 15 mg/kg IV on the same day, every 3 weeks, or sorafenib orally twice daily. In July 2020, it was approved in the United States...
Using this method has contributed to the discovery of the drug Sorafenib (Nexavar). Sorafenib is used as medication to treat multiple types of cancers, including...
greater extent than some other classes of birth control pills. Nexavar (sorafenib) is a kinase inhibitor used in the treatment of liver cancer (hepatocellular...
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