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Son of Sevenless information


son of sevenless homolog 1
Identifiers
SymbolSOS1
Alt. symbolsGINGF
NCBI gene6654
HGNC11187
OMIM182530
RefSeqNM_005633
UniProtQ07889
Other data
LocusChr. 2 p21
Search for
StructuresSwiss-model
DomainsInterPro
son of sevenless homolog 2
Identifiers
SymbolSOS2
NCBI gene6655
HGNC11188
OMIM601247
RefSeqNM_006939
UniProtQ07890
Other data
LocusChr. 14 q21
Search for
StructuresSwiss-model
DomainsInterPro

In cell signalling, Son of Sevenless (SOS) refers to a set of genes encoding guanine nucleotide exchange factors that act on the Ras subfamily of small GTPases.

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Son of Sevenless

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signalling, Son of Sevenless (SOS) refers to a set of genes encoding guanine nucleotide exchange factors that act on the Ras subfamily of small GTPases...

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SOS1

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Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene. SOS1 is a guanine nucleotide exchange factor (GEF) which interacts...

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List of unusual biological names

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This is a list of unusual biological names, given to biological inventions and discoveries. One might consider the listed names unusual due to their containing...

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Ribosomal s6 kinase

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inhibitor of cdc2. RSK phosphorylation of SOS1 (Son of Sevenless) at Serines 1134 and 1161 creates 14-3-3 docking site. This interaction of phospho SOS1...

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Ras GTPase

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nucleotide binding pocket of Ras and reloads the spring. Thus GEFs facilitate Ras activation. Well known GEFs include Son of Sevenless (Sos) and cdc25 which...

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GRAP

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of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless...

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Guanine nucleotide exchange factor

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a role in regulating these pathways through their activation of GTPases. Son of sevenless (SOS1) is an important GEF in the cell growth-regulatory MAPK/ERK...

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RhoGEF domain

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J (October 1998). "Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein". Cell. 95 (2): 259–68. doi:10...

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GRB2

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2000). "Engagement of the T lymphocyte antigen receptor regulates association of son-of-sevenless homologues with the SH3 domain of phospholipase Cgamma1"...

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PLCG1

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2000). "Engagement of the T lymphocyte antigen receptor regulates association of son-of-sevenless homologues with the SH3 domain of phospholipase Cgamma1"...

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Roundabout family

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motifs of the Robo receptors. In Drosophila, several signaling proteins downstream of Robo1 have been identified, including Enabled, Son of Sevenless (SOS)...

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SOS2

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SOS2 may refer to: Son of Sevenless, a set of encoding genes Special ordered set of type 2, a structure in discrete optimization This disambiguation page...

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BAG3

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2000). "Engagement of the T lymphocyte antigen receptor regulates association of son-of-sevenless homologues with the SH3 domain of phospholipase Cgamma1"...

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PACSIN1

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factor mammalian Son-of-sevenless interacts with PACSIN 1/syndapin I, a regulator of endocytosis and the actin cytoskeleton". The Journal of Biological Chemistry...

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Hereditary gingival fibromatosis

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SOS1, son-of-sevenless gene, is responsible for this disease. SOS1 is a guanine nucleotide-exchange factor that functions in the transduction of signals...

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Utpal Banerjee

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public university in the state of California. Earlier work from Banerjee’s laboratory identified the Son of sevenless (Sos) gene that links RTKs to the...

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