Short tandem repeat (STR) analysis on a simplified model using polymerase chain reaction (PCR): First, a DNA sample undergoes PCR with primers targeting certain STRs (which vary in lengths between individuals and their alleles). The resultant fragments are separated by size (such as electrophoresis).[1]A partial human STR profile obtained using the Applied Biosystems Identifiler kit
Shorttandemrepeat (STR) analysis is a common molecular biology method used to compare allele repeats at specific loci in DNA between two or more samples. A short tandem repeat is a microsatellite with repeat units that are 2 to 7 base pairs in length, with the number of repeats varying among individuals, making STRs effective for human identification purposes.[2] This method differs from restriction fragment length polymorphism analysis (RFLP) since STR analysis does not cut the DNA with restriction enzymes. Instead, polymerase chain reaction (PCR) is employed to discover the lengths of the short tandem repeats based on the length of the PCR product.
^Image by Mikael Häggström, MD, using following source image: Figure 1 - available via license: Creative Commons Attribution 4.0 International", from the following article: Roberta Sitnik, Margareth Afonso Torres, Nydia Strachman Bacal, João Renato Rebello Pinho (2006). "Using PCR for molecular monitoring of post-transplantation chimerism". Einstein (Sao Paulo). 4 (2).{{cite journal}}: CS1 maint: multiple names: authors list (link)
^Butler, John M. (4 August 2011). Advanced Topics in Forensic DNA Typing: Methodology. San Diego: Elsevier Academic Press. pp. 99–100. ISBN 9780123745132.
Short tandem repeat (STR) analysis is a common molecular biology method used to compare allele repeats at specific loci in DNA between two or more samples...
technologies used in DNA profiling and analysis. However, as technology has evolved, new technologies, like STR, emerged and took the place of older technology...
Short tandem repeat (STR) analysis is the primary type of forensic DNA analysis performed in modern DNA laboratories. STRanalysis builds upon RFLP and...
identification based on DNA analysis using short tandem repeats (STRs). Promega was the first company to provide kits for STRanalysis of single loci. Along...
widely used for DNA profiling in kinship analysis (most commonly in paternity testing). Paternally inherited Y-STRs (microsatellites on the Y chromosome)...
Bosch, Elena et al. "Genetic structure of north-west Africa revealed by STRanalysis." European Journal of Human Genetics (2000) 8, 360–366. Pg. 365 "Morocco...
tandem repeat (STR) tests. Analysis of RFLP variation in genomes was formerly a vital tool in genome mapping and genetic disease analysis. If researchers...
the roots of teeth. For most forensic DNA samples, STRanalysis of autosomal short tandem repeats (STR) is performed in an attempt to individualize the...
Principal component analysis (PCA) is a linear dimensionality reduction technique with applications in exploratory data analysis, visualization and data...
canes were a symbol of status in ancient Egypt. Genetic testing through STRanalysis rejected the hypothesis of gynecomastia and craniosynostoses (e.g., Antley–Bixler...
highly degraded evidence that would not be beneficial for STRanalysis could be used in mtDNA analysis. mtDNA may be present in bones, teeth, or hair, which...
single-strand conformation polymorphism (SSCP) heteroduplex analysis, and short tandem repeat (STR) analysis. Resolving DNA fragments according to differences in...
DNA profiling Short Tandem Repeat STRanalysisSTR multiplex system Snpstr Y-STR List of Y-STR markers List of X-STR markers Strbase List of online databases...
Cerutti, N; Piazza, A; Inturri, S; Torre, C (2008). "Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample". International...
Africa: High-resolution SNP and STRanalysis in Tunisia and Morocco populations Bosch et al. 2001, High-resolution analysis of humanY-chromosome variation...
genotyped 218 unrelated males from the Igbo, Hausa and Yoruba tribes using X-STRanalysis, found that when studying the genetic affinity, no significant differences...
Tajikistan and various Uzbeks in different Central Asian countries. STR loci analysis by Zhan et. al. (2018) shows that the closest relative of Dongxiang...
through additional cycles of PCR amplification. Touch DNA relies on the STRanalysis of cells collected off of objects. Upon collection, the cells' DNA is...
2007, 2015) has been based on STRanalysis (8 and 10 loci, respectively) and recent studies clearly indicate that the STR-based age calculations tend to...
including isoenzyme analysis, human lymphocyte antigen (HLA) typing, chromosomal analysis, karyotyping, morphology and STRanalysis. One significant cell-line...
criminal and “no-suspect” casework. The Laboratory offers STRanalysis and Y-STRanalysis with each of the commercial kits commonly used in the US. The...
study led by the Egyptian Army Major General Doctor Tarek Taha conducted STRanalysis in 2020 between the two main Egyptian ethnic groups, Muslims and Christians...
electrophoresis using the ABI Prism 310 and 3100 genetic analyzers for STRanalysis" (PDF). Electrophoresis. 25 (10–11): 1397–412. doi:10.1002/elps.200305822...
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