negative regulation of cytosolic calcium ion concentration
transmembrane transport
release of sequestered calcium ion into cytosol
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
6263
20192
Ensembl
ENSG00000198838
ENSMUSG00000057378
UniProt
Q15413
A2AGL3
RefSeq (mRNA)
NM_001036 NM_001243996
NM_177652 NM_001319156
RefSeq (protein)
NP_001027 NP_001230925
NP_001306085
Location (UCSC)
Chr 15: 33.31 – 33.87 Mb
Chr 2: 112.46 – 113.05 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Ryanodine receptor 3 is one of a class of ryanodine receptors and a protein that in humans is encoded by the RYR3 gene.[5] The protein encoded by this gene is both a calcium channel and a receptor for the plant alkaloid ryanodine. RYR3 and RYR1 control the resting calcium ion concentration in skeletal muscle.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000198838 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000057378 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Sorrentino V, Giannini G, Malzac P, Mattei MG (Feb 1994). "Localization of a novel ryanodine receptor gene (RYR3) to human chromosome 15q14-q15 by in situ hybridization". Genomics. 18 (1): 163–5. doi:10.1006/geno.1993.1446. PMID 8276408.
^Perez CF, López JR, Allen PD (March 2005). "Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle". Am. J. Physiol., Cell Physiol. 288 (3): C640–9. doi:10.1152/ajpcell.00407.2004. PMID 15548569. S2CID 30888541.
and 24 Related for: Ryanodine receptor 3 information
Ryanodinereceptor3 is one of a class of ryanodinereceptors and a protein that in humans is encoded by the RYR3 gene. The protein encoded by this gene...
Ryanodinereceptors (RyR for short) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons...
Ryanodinereceptor 2 (RYR2) is one of a class of ryanodinereceptors and a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2...
Ryanodinereceptor 1 (RYR-1) also known as skeletal muscle calcium release channel or skeletal muscle-type ryanodinereceptor is one of a class of ryanodine...
insecticide. The compound has extremely high affinity to the open-form ryanodinereceptor, a group of calcium channels found in skeletal muscle, smooth muscle...
"Structural and functional conservation of key domains in InsP3 and ryanodinereceptors". Nature. 483 (7387): 108–112. Bibcode:2012Natur.483..108S. doi:10...
located on the long arm of chromosome 19 (19q13.2) involving the ryanodinereceptor. More than 25 different mutations in this gene are linked with malignant...
which encodes a protein included in an ion channel known as the ryanodinereceptor; this channel releases calcium from a cell's internal calcium store...
conformational changes that allosterically activates the ryanodinereceptors). As ryanodinereceptors open, Ca2+ is released from the sarcoplasmic reticulum...
Chlorantraniliprole opens muscular calcium channels, in particular the ryanodinereceptor, rapidly causing paralysis and ultimately death of sensitive species...
cytoplasm. In heart muscle cells this increase in Ca2+ activates the ryanodinereceptor-operated channel on the SR, results in further increases in Ca2+ through...
the LTCC and the ryanodinereceptor to increase intracellular calcium levels and cause contraction. Beta-blockade of the β1 receptor will inhibit cAMP...
venom of the scorpion Hadrurus gertschi. Hadrucalcin modifies the Ryanodinereceptor channels RyR1 and RyR2, found in the sarcoplasmic reticulum, to a...
peptide (CPP); it binds with high affinity and specificity to skeletal ryanodinereceptor 1 (RYR1) of the sarcoplasmic reticulum, thereby triggering calcium...
with the release of calcium by binding to the ryanodinereceptor and blocking the endogenous ligand ryanodine by competitive inhibition. Muscle that contracts...
hydrophobic section and it forms a quaternary complex with the cardiac ryanodinereceptor (RYR2), calsequestrin (CASQ2) and junctin proteins. The luminal (inner...
through an ion channel within the membrane of the SR, known as a ryanodinereceptor (RyR), which opens upon activation. This process is important as it...
ryanodinereceptors present on the sarcoplasmic reticulum. The inward flow of calcium from the L-type calcium channels activates ryanodinereceptors to...
transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein...
flecainide is useful to break a tachyarrhythmia. Flecainide also inhibits ryanodinereceptor 2 (RyR2), a major regulator of sarcoplasmic release of stored calcium...
of contributed programs for IBM computers. Spla/ryanodinereceptor domain and socs box containing 3, a protein encoded by the SPSB3 gene This disambiguation...
Global Information
