"Modulon" redirects here. For the spasmolytic, see Modulon (drug). For the birth control pill, see Ethinylestradiol/desogestrel.
In molecular genetics, a regulon is a group of genes that are regulated as a unit, generally controlled by the same regulatory gene that expresses a protein acting as a repressor or activator. This terminology is generally, although not exclusively, used in reference to prokaryotes, whose genomes are often organized into operons; the genes contained within a regulon are usually organized into more than one operon at disparate locations on the chromosome.[1] Applied to eukaryotes, the term refers to any group of non-contiguous genes controlled by the same regulatory gene.[2]
A modulon is a set of regulons or operons that are collectively regulated in response to changes in overall conditions or stresses, but may be under the control of different or overlapping regulatory molecules. The term stimulon is sometimes used to refer to the set of genes whose expression responds to specific environmental stimuli.[1]
^ abLengeler, Joseph W.; Postma, P.W. (1999). "Global Regulatory Networks and Signal Transduction Pathways". In Lengeler, Joseph W.; Drews, Gerhart; Schlegel, Hans G. (eds.). Biology of the prokaryotes. Stuttgart: Thieme. pp. 498–9. ISBN 9781444313307.
^Regulon at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
In molecular genetics, a regulon is a group of genes that are regulated as a unit, generally controlled by the same regulatory gene that expresses a protein...
The Phosphate (Pho) regulon is a regulatory mechanism used for the conservation and management of inorganic phosphate within the cell. It was first discovered...
In bacterial genetics, the mal regulon is a regulon - or group of genes under common regulation - associated with the catabolism of maltose and maltodextrins...
In DNA repair, the Ada regulon is a set of genes whose expression is essential to adaptive response (also known as "Ada response", hence the name), which...
RegulonDB is a database of the regulatory network of gene expression in Escherichia coli K-12. RegulonDB also models the organization of the genes in transcription...
The Nif regulon is a set of seven operons used to regulate nitrogen fixation in the coliform bacterium Klebsiella pneumoniae under anaerobic and microaerophilic...
Mol. Microbiol. Biotechnol. 4:263-268. 2002. A Reassessment of the FNR Regulon and Transcriptomic Analysis of the Effects of Nitrate, Nitrite, NarXL,...
are coded for on the cys regulon. The integration of sulfur is positively regulated by CysB. Effective inducers of this regulon are N-acetyl-serine (NAS)...
object, an asteroid or comet that could potentially collide with Earth Pho regulon, a bacterial phosphate regulatory mechanism Pho4, a basic helix-loop-helix...
Bordetella petrii. Untersuchungen zur genomischen Variabilität und zum Bvg Regulon Melanie Lechner Würzburg, 2008 International Journal of Systematic and...
of structural genes of the SoxRS regulon. The transcriptional factor OxyR regulates the expression of OxyR regulon. H2O2 oxidizes the transcriptional...
"Staphylococcus aureus competence genes: mapping of the SigH, ComK1 and ComK2 regulons by transcriptome sequencing". Molecular Microbiology. 94 (3): 557–579....
The gene rpoS (RNA polymerase, sigma S, also called katF) encodes the sigma factor sigma-38 (σ38, or RpoS), a 37.8 kD protein in Escherichia coli. Sigma...
and scarlet fever. Functional studies suggest that the ropB multigene regulon is responsible for not only global regulation of virulence but also a wide...
purine catabolic pathway in Bacillus subtilis and evidence for a novel regulon controlled by the PucR transcription activator". Journal of Bacteriology...
Ancestry. Retrieved 26 December 2017. Bhat PJ (2 March 2008). Galactose Regulon of Yeast: From Genetics to Systems Biology. Springer Science & Business...
29111273 Claverys JP, Prudhomme M, Martin B (2006). "Induction of competence regulons as a general response to stress in gram-positive bacteria". Annu. Rev....
AT transition mutations and also to induce genes of the OxyR and SoxRS regulons suggesting further that bile salts specifically cause oxidative DNA damage...
expression: evidence for multiple positive regulators of the phosphate regulon in Escherichia coli". Genetics. 96 (2): 353–66. doi:10.1093/genetics/96...
Operons are related to regulons, stimulons and modulons; whereas operons contain a set of genes regulated by the same operator, regulons contain a set of genes...
Ada Health, a German medical technology company ADA (disambiguation) Ada regulon, an Escherichia coli adaptive response protein Adah (disambiguation) Adha...
of Sports, the highest governing body for sports in Norway Nif gene Nif regulon Neuroscience Information Framework, an inventory of web-based neurosciences...
related oral streptococci, is subjected to acid stress, the competence regulon is induced, leading to resistance to being killed by acid. As pointed out...
"Detection of other microbial species by Salmonella: expression of the SdiA regulon". Journal of Bacteriology. 185 (4): 1357–1366. doi:10.1128/JB.185.4.1357-1366...
Global Information