Recombination signal sequences are conserved sequences of noncoding DNA that are recognized by the RAG1/RAG2 enzyme complex during V(D)J recombination in immature B cells and T cells.[1] Recombination signal sequences guide the enzyme complex to the V, D, and J gene segments that will undergo recombination during the formation of the heavy and light-chain variable regions in T-cell receptors and immunoglobulin molecules.[1]
^ abOwen, Judith A.; Punt, Jenni; Stranford, Sharon A. (2013). Kuby Immunology. New York: W.H. Freeman and Company. pp. 233–235.
and 21 Related for: Recombination signal sequences information
Recombinationsignalsequences are conserved sequences of noncoding DNA that are recognized by the RAG1/RAG2 enzyme complex during V(D)J recombination...
recombination of both alleles in highly expressed GATA3 cells. V𝛽 Recombinationsignalsequences (RSSs) with poor qualities suppressed one allele's expression...
Uptake signalsequences (USS) are short DNA sequences preferentially taken up by competent bacteria of the family Pasteurellaceae (e.g., Haemophilus influenzae)...
homologous recombinational repair (HRR). Homologous recombination also produces new combinations of DNA sequences during meiosis, the process by which eukaryotes...
phase during V(D)J recombination. This complex can make double-strand breaks by cleaving DNA at conserved recombinationsignalsequences (RSS). The other...
activity also requires RAG-2. The RAG-1/2 complex recognizes recombinationsignalsequences (RSSs) that flank the V, D and J regions in the genes that encode...
methods of genetic recombination (such as molecular cloning) that bring together genetic material from multiple sources, creating sequences that would not...
"The Recombination Hypothesis" is the 13th episode of the fifth season, as well as the 100th episode overall, of the American television sitcom The Big...
G. E. (December 1991). "Mouse kappa light-chain recombinationsignalsequences mediate recombination more frequently than do those of lambda light chain"...
During V(D)J recombination, the RAG complex (made up of RAG-1 and RAG-2 complexed with HMG1 or HMG2) binds to two recombinationsignalsequences (RSSs); the...
Illegitimate recombination, or nonhomologous recombination, is the process by which two unrelated double stranded segments of DNA are joined. This insertion...
belcheri (Chinese lancelet). The TIRs are structurally similar to Recombinationsignalsequences (RSS). The heptamer bears the consensus CACWRTG, while the nonamer...
Recombination occurs in a specific region of the gene that is located between two conserved sequence motifs called recombinationsignalsequences. Each...
are molecular breeding which relies on homologous recombination or the similarity of the DNA sequences, restriction enzymes which rely on common restriction...
sequence, which then defines one or more protein sequences. The relationship between the nucleotide sequences of genes and the amino-acid sequences of...
carrier will definitely get the disease. The first report of Alu-mediated recombination causing a prevalent inherited predisposition to cancer was a 1995 report...
sites and sequences within their respective enzymes. However these drugs can quickly become ineffective due to the fact that the gene sequences that code...
newly synthesized retroviral DNA sequence that is a recombinant between the two parental genomes. This recombination is most obvious when it occurs between...
also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production...
that can integrate itself into the bacterial chromosome by homologous recombination) with a length of about 100 kb. It carries its own origin of replication...
through the energy levels to the ground state, giving rise to a sequence of recombination spectral lines spread across the electromagnetic spectrum. The...
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