RNA polymerase II cis-regulatory region sequence-specific DNA binding
ATP-dependent activity, acting on DNA
histone binding
histone deacetylase binding
protein binding
nucleosomal DNA binding
histone deacetylase activity
Cellular component
NuRD complex
ESC/E(Z) complex
CAF-1 complex
Sin3 complex
nucleoplasm
NURF complex
nucleus
cytosol
protein-containing complex
Biological process
chromatin remodeling
regulation of transcription, DNA-templated
CENP-A containing chromatin assembly
transcription, DNA-templated
regulation of cell cycle
DNA replication-dependent chromatin assembly
DNA replication
negative regulation of gene expression, epigenetic
cell cycle
negative regulation of cell population proliferation
regulation of signal transduction by p53 class mediator
histone deacetylation
response to growth hormone
negative regulation of G0 to G1 transition
chromatin organization
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
5928
19646
Ensembl
ENSG00000162521
ENSMUSG00000057236
UniProt
Q09028
Q60972
RefSeq (mRNA)
NM_005610 NM_001135255 NM_001135256
NM_009030
RefSeq (protein)
NP_001128727 NP_001128728 NP_005601
NP_033056
Location (UCSC)
Chr 1: 32.65 – 32.69 Mb
Chr 4: 129.2 – 129.23 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000162521 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000057236 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Qian YW, Wang YC, Hollingsworth RE Jr, et al. (September 1993). "A retinoblastoma-binding protein related to a negative regulator of Ras in yeast". Nature. 364 (6438): 648–52. Bibcode:1993Natur.364..648Q. doi:10.1038/364648a0. PMID 8350924. S2CID 4303062.
^Barak O, Lazzaro MA, Lane WS, et al. (November 2003). "Isolation of human NURF: a regulator of Engrailed gene expression". EMBO J. 22 (22): 6089–100. doi:10.1093/emboj/cdg582. PMC 275440. PMID 14609955.
Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene. This gene encodes a ubiquitously...
Ezh1 or Ezh2 (SET domain with histone methyltransferase activity) and Rbbp4 (histone binding domain). PRC2 can bind to H3K27me3 and repress neighboring...
Histone-binding protein RbAp48 (also known as RBBP4 or NURF55), encoded by the RBBP4 gene in humans. RbAp48, also known as RBBP4 gene, encodes a nuclear protein, which...
dimerization partners of E2F; and MuvB, which is a complex of LIN9/37/52/54 and RBBP4. Genes encoding the MuvB complex were originally identified from loss-of-function...
GTPase-activating protein RANBP2 RANBP2/NUP358 RAN Binding Protein 2 RBBP4RBBP4 Histone-binding protein RBBP4 RBFOX1 RBFOX1 RNA binding protein fox-1 homolog yes RBFOX2...
shown to interact with Methyl-CpG-binding domain protein 2, MBD3, RBBP7 and RBBP4. ENSG00000261992 GRCh38: Ensembl release 89: ENSG00000143614, ENSG00000261992...
N-terminus (N-12a.a.), SALL4 binds to retinoblastoma binding protein 4 (RBBP4), a subunit of the nucleosome remodeling and histone deacetylation (NuRD)...
Global Information
