A volume rendered brain QSM acquired at 3 Tesla and reconstructed with morphology enabled dipole inversion (MEDI).
Quantitative susceptibility mapping (QSM) provides a novel contrast mechanism in magnetic resonance imaging (MRI) different from traditional susceptibility weighted imaging.[1][2][3][4][5]
The voxel intensity in QSM is linearly proportional to the underlying tissue apparent magnetic susceptibility, which is useful for chemical identification and quantification of specific biomarkers including iron, calcium, gadolinium, and super paramagnetic iron oxide (SPIO) nano-particles. QSM utilizes phase images, solves the magnetic field to susceptibility source inverse problem, and generates a three-dimensional susceptibility distribution. Due to its quantitative nature and sensitivity to certain kinds of material, potential QSM applications include standardized quantitative stratification of cerebral microbleeds and neurodegenerative disease, accurate gadolinium quantification in contrast enhanced MRI, and direct monitoring of targeted theranostic drug biodistribution in nanomedicine.
^1st International Workshop on MRI Phase Contrast and Quantitative Susceptibility Mapping, Jena (2011)
^2nd International Workshop on MRI Phase Contrast & Quantitative Susceptibility Mapping, Cornell (2013)
^3rd International Workshop on MRI Phase Contrast & Quantitative Susceptibility Mapping, Duke (2014)
^4th International Workshop on MRI Phase Contrast & Quantitative Susceptibility Mapping, Graz (2016)
^Wang, Yi (2014). "Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker". Magnetic Resonance in Medicine. 73 (1): 82–101. doi:10.1002/mrm.25358. PMC 4297605. PMID 25044035.
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environmental background. If many alleles are required to increase susceptibility to a disease, the odds are low that the necessary combination of alleles...
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PMC 3105340. PMID 21326233. Drayton, M.; Noben-Trauth, K. (2006). "Mappingquantitative trait loci for hearing loss in Black Swiss mice". Hearing Research...
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