Genomic loci that explain variation in mRNA expression levels
Expression quantitative trait loci (eQTLs) are genomic loci that explain variation in expression levels of mRNAs.[1][2]
^Rockman MV, Kruglyak L (November 2006). "Genetics of global gene expression". Nature Reviews. Genetics. 7 (11): 862–72. doi:10.1038/nrg1964. PMID 17047685. S2CID 150368.
^Nica, Alexandra C.; Dermitzakis, Emmanouil T. (2013). "Expression quantitative trait loci: Present and future". Philosophical Transactions of the Royal Society B: Biological Sciences. 368 (1620): 20120362. doi:10.1098/rstb.2012.0362. PMC 3682727. PMID 23650636.
and 23 Related for: Expression quantitative trait loci information
A quantitativetrait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitativetrait in the phenotype of a population of...
Toste CC, Robertson MJ, Morgan JE, et al. (November 2018). "Expressionquantitativetraitloci in the developing human brain and their enrichment in neuropsychiatric...
point to "length of stem". Analysis of quantitativetraitloci, or QTLs, is a more recent addition to quantitative genetics, linking it more directly to...
(gonosomal loci) Sex-limited phenotype expression (e.g., cryptorchism) Inheritance through the maternal line (in case of mitochondrial DNA loci) Inheritance...
studies. They are also studied with statistical techniques like quantitativetraitloci(QTL) mapping, and genome-wide association studies(GWAS) on a large...
single-cell expressionquantitativetraitloci (ie, genomic variants with strong statistical associations with changes in gene expression within specific...
showed that if multiple Mendelian factors were involved in the expression of an individual trait, they could produce the diverse results observed, thus demonstrating...
et al. (2012). "Loci nominally associated with autism from genome-wide analysis show enrichment of brain expressionquantitativetraitloci but not lymphoblastoid...
continuous blend. Blending of traits in the progeny is now explained by the action of multiple genes with quantitative effects. Another theory that had...
and influence of putatively associated genetic loci (usually single-nucleotide polymorphisms) on the trait. This can lead to underestimation of heritability...
In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic information...
simultaneous analysis of the expression of thousands of different genes. Quantitative PCR may also be used to analyze gene expression as a result of changes...
increase the type-1 error rate and reduce the power to map human quantitativetraitloci (QTL). While linkage analysis was successfully used to identify...
heterotic if its traits are enhanced as a result of mixing the genetic contributions of its parents. The heterotic offspring often has traits that are more...
mechanisms that each have small effects on the overall resistance trait. Quantitative resistance is often contrasted to ETI resistance mediated by single...
PMC 16650. PMID 10859367. Hoeschele I (2004-07-15). "Mapping QuantitativeTraitLoci in Outbred Pedigrees". Handbook of Statistical Genetics. John Wiley...
Introgression lines allow the study of quantitativetraitloci, but also the creation of new varieties by introducing exotic traits. Lineage fusion is an extreme...
that control one trait at one specific locus. Epistatic variance involves an interaction between different alleles in different loci. Heritability refers...
than one direction. In particular, if the trait is quantitative and univariate then both higher and lower trait levels are favoured. Disruptive selection...
regulatory elements, and relationship to quantitativetraitloci, of sorghum genes with rhizome-enriched expression". Plant Physiology. 142 (3): 1148–1159...
molecular biology, epistasis started to be studied in relation to quantitativetraitloci (QTL) and polygenic inheritance. The effects of genes are now commonly...
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