Pyrococcus furiosus is a heterotrophic, strictly anaerobic, extremophilic, model species of archaea. It is classified as a hyperthermophile because it thrives best under extremely high temperatures, and is notable for having an optimum growth temperature of 100 °C (a temperature that would destroy most living organisms).[1]P. furiosus belongs to the Pyrococcus genus, most commonly found in extreme environmental conditions of hydrothermal vents. It is one of the few prokaryotic organisms that has enzymes containing tungsten, an element rarely found in biological molecules.
Pyrococcus furiosus has many potential industrial applications, owing to its unique thermostable properties. P. furiosus is used in the process of DNA amplification by way of polymerase chain reaction (PCR) because of its proofreading activity. Utilizing P. furiosus in PCR DNA amplification instead of the traditionally used Taq DNA polymerase allows for a significantly more accurate process.[2] The thermodynamic stability of P. furiosus' enzymes is useful in the creation of diols for laboratory and industrial purposes. Certain superoxide dismutases found in P. furiosus can be introduced into plants to increase their tolerance in environmentally stressful conditions and ultimately their survival.[3]
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and 27 Related for: Pyrococcus furiosus information
biological molecules. Pyrococcusfuriosus has many potential industrial applications, owing to its unique thermostable properties. P. furiosus is used in the...
Pyrococcus is a genus of Thermococcaceaen archaean. Pyrococcus has similar characteristics of other thermoautotrophican archaea such as Archaeoglobus,...
polymerase is an enzyme found in the hyperthermophilic archaeon Pyrococcusfuriosus, where it functions to copy the organism's DNA during cell division...
and hyperthermophiles are found. The hyperthermophilic archaean Pyrococcusfuriosus was described for the first time when it was isolated from sediments...
heat-stable enzyme of this family found in the hyperthermophilic archaeon Pyrococcusfuriosus. Detailed classification divides family B in archaea into B1, B2...
acids from C16 to C22 were found in an hyperthermophilic archaeon, Pyrococcusfuriosus. Short and medium chain (up to 11 carbon atoms) dioic acids have...
Illinois reported using a prokaryotic Argonaute protein taken from Pyrococcusfuriosus (PfAgo) along with guide DNA to edit DNA in vitro as artificial restriction...
Google Chrome, and Safari. Crystal structure of an H/ACA box RNP from Pyrococcusfuriosus Highlighting two salt bridges in hemoglobin tetramer (hemo group...
of informations about sugar catabolism came from observation on Pyrococcusfuriosus. It grows on many different sugars such as starch, maltose, and cellobiose...
a CRISPR-Cas system that targets foreign RNA was later found in Pyrococcusfuriosus. A 2010 study showed that CRISPR-Cas cuts both strands of phage and...
oceanic crust 110 °C (230 °F) to 121 °C (250 °F) Pyrolobus fumarii, Pyrococcusfuriosus Low temperature Ice −20 °C (−4 °F) to −25 °C (−13 °F) Rhodotorula...
oxidoreductases. AOR is found in hyperthermophillic archaea, Pyrococcusfuriosus. The archaeons Pyrococcus ES-4 strain and Thermococcus ES-1 strain differ by their...
2014). "DNA polymerase hybrids derived from the family-B enzymes of Pyrococcusfuriosus and Thermococcus kodakarensis: improving performance in the polymerase...
thermostable DNA polymerases, such as the Pfu DNA polymerase from Pyrococcusfuriosus, revolutionized molecular biology by allowing the polymerase chain...
Leptospirillum ferrooxidans. In other studies the iron-reducing archaea Pyrococcusfuriosus were shown to produce hydrogen gas which can then be used as fuel...
(October 2004). "A proposal to rename the hyperthermophile Pyrococcus woesei as Pyrococcusfuriosus subsp. woesei". Archaea. 1 (4): 277–83. doi:10.1155/2004/513563...
pasteurianum PDB: 1VCX – Neutron diffraction structure of rubredoxin from Pyrococcusfuriosus InterPro: IPR001052 – InterPro entry for rubredoxin A little iron-sulfur...
2002. Among the other extremophiles discovered by Stetter has been Pyrococcusfuriosus, which was found on the Italian island of Vulcano in 1981. This extremophile...
to culture contamination. Thermococcus kodakarensis, Pyrococcus abyssi, and Pyrococcusfuriosus are the Thermococcales models. This order is known for...
Pfu DNA polymerase, which is extracted from Pyrococcusfuriosus; Pwo, which is extracted from Pyrococcus woesii; Q5 polymerase, with 280x higher fidelity...
(December 2004). "Rubrerythrin from the Hyperthermophilic Archaeon Pyrococcusfuriosus Is a Rubredoxin-Dependent, Iron-Containing Peroxidase". Journal of...
Glyceraldehyde-3-phosphate ferredoxin oxidoreductase (GAPOR) in Pyrococcusfuriosus A wtp system is known to selectively transport tungsten in archaea:...
University of Illinois reported using an Argonaute protein taken from Pyrococcusfuriosus (PfAgo) along with guide DNA to edit DNA in vitro as artificial restriction...
Left: A full-length Argonaute protein from the archaea species Pyrococcusfuriosus. Right: The PIWI domain of an Argonaute protein in complex with double-stranded...
identified in an analogous role in enzymes from some archaea, such as Pyrococcusfuriosus. In contrast, and unusually for a first-row d-block transition metal...
2004). "Substrate specificity and mechanism from the structure of Pyrococcusfuriosus galactokinase". Journal of Molecular Biology. 337 (2): 387–98. doi:10...
anaerobes), and is only obligated in hyperthermophilic archaea such as P. furiosus. Although research into the specific enzyme complexes in which tungsten...
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