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Pyriproxyfen information


Pyriproxyfen
Chemical structure of pyriproxyfen
Names
IUPAC names
4-Phenoxyphenyl (R/S)-2-(2-pyridyloxy)propyl ether
2-[1-(4-Phenoxyphenoxy)propan-2-yloxy]pyridine
Identifiers
CAS Number
  • 95737-68-1 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:39260 checkY
ChemSpider
  • 82851 checkY
ECHA InfoCard 100.102.814 Edit this at Wikidata
KEGG
  • C18605 checkY
PubChem CID
  • 91753
UNII
  • 3Q9VOR705O ☒N
CompTox Dashboard (EPA)
  • DTXSID1032640 Edit this at Wikidata
InChI
  • InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 checkY
    Key: NHDHVHZZCFYRSB-UHFFFAOYSA-N checkY
  • InChI=1/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3
    Key: NHDHVHZZCFYRSB-UHFFFAOYAG
SMILES
  • O(c1ncccc1)C(COc3ccc(Oc2ccccc2)cc3)C
Properties
Chemical formula
C20H19NO3
Molar mass 321.376 g·mol−1
Appearance Colorless crystals[1]
Density 1.2 g/cm3[1]
Melting point 48–50 °C (118–122 °F; 321–323 K)[2]
Boiling point 318 °C (604 °F; 591 K)[2]
Solubility in water
0.367 mg/L[2]
Pharmacology
ATCvet code
QP53AX23 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Pyriproxyfen is a pesticide which is found to be effective against a variety of insects.[3] It was introduced to the US in 1996, to protect cotton crops against whitefly. It has also been found useful for protecting other crops.[4] It is also used as a prevention for flea control on household pets, for killing indoor and outdoor ants and roaches.[5] Methods of application include aerosols, bait, carpet powders, foggers, shampoos and pet collars.[6]

Pyriproxyfen is a juvenile hormone analog and an insect growth regulator.[7] It prevents larvae from developing into adulthood and thus rendering them unable to reproduce.[8]

In the US, pyriproxyfen is often marketed under the trade name Nylar.[9] In Europe, pyriproxyfen is known under the brand names Cyclio (Virbac)[10] and Exil Flea Free TwinSpot (Emax).

  1. ^ a b "Pyriproxifen". National Institute for Occupational Safety and Health.
  2. ^ a b c "WHO Specifications and Evaluations for Public Health Pesticides: Pyriproxifen" (PDF). Archived from the original (PDF) on July 27, 2009.
  3. ^ Ishaaya, I; Horowitz, AR (1995). "Pyriproxyfen, a Novel Insect Growth Regulator for Controlling Whiteflies : Mechanisms and Resistance Management". Pestic. Sci. 43 (3): 227–232. doi:10.1002/ps.2780430308.
  4. ^ Devillers, James (May 6, 2013). Juvenile Hormones and Juvenoids: Modeling Biological Effects and Environmental Fate. CRC Press. pp. 108–126. ISBN 9781466513228.
  5. ^ Maddison, Jill E.; Page, Stephen W.; Church, David (2008). Small Animal Clinical Pharmacology. Elsevier Health Sciences. p. 226. ISBN 9780702028588.
  6. ^ "Federal Register | Pyriproxyfen; Pesticide Tolerances". www.federalregister.gov. Retrieved 2016-02-28.
  7. ^ "PyriproxyfenGeneral Fact Sheet". National Pesticide Information Center, Oregon State University Extension Services.
  8. ^ Szabo, Liz (February 16, 2016). "Scientists debunk theory linking pesticide, not Zika, to birth defects". USA Today. Retrieved February 16, 2016.
  9. ^ Goss, G. Robert (1997). Pesticide Formulations and Application Systems. ASTM International. pp. 87–93. ISBN 9780803124691.
  10. ^ Rock, Amanda; Bowden, Sally; Cousquer, Glen (2007). Veterinary Pharmacology: A Practical Guide for the Veterinary Nurse. Elsevier Health Sciences. p. 96. ISBN 9780750688628.

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