Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Piperonyl butoxide (PBO) is a pale yellow to light brown liquid[1] organic compound used as an adjuvant component of pesticide formulations for synergy. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone.[2]
It is a semisynthetic derivative of safrole and is produced from the condensation of the sodium salt of 2-(2-butoxyethoxy) ethanol and the chloromethyl derivative of hydrogenated safrole (dihydrosafrole).[3][4]
Although this route of synthesis has faced a lot of criticism in recent times. The new route of synthesis is through 1,2-Methylenedioxybenzene, developed by The Anthea Group and patented in 2019.
^National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.[page needed]
^National Pesticide Information Center – Piperonyl Butoxide General Fact Sheet
^Metcalf, Robert L. (2000). "Insect Control". Ullmann's Encyclopedia of Industrial Chemistry. doi:10.1002/14356007.a14_263. ISBN 978-3-527-30385-4.
^Osimitz, Thomas G. (2010). "The Safety Assessment of Piperonyl Butoxide". Hayes' Handbook of Pesticide Toxicology. pp. 2127–2151. doi:10.1016/B978-0-12-374367-1.00099-9. ISBN 978-0-12-374367-1.
and 29 Related for: Piperonyl butoxide information
Piperonylbutoxide (PBO) is a pale yellow to light brown liquid organic compound used as an adjuvant component of pesticide formulations for synergy. That...
often considered an organic insecticide when it is not combined with piperonylbutoxide or other synthetic adjuvants. Their insecticidal and insect-repellent...
It is a precursor in the synthesis of the insecticide synergist piperonylbutoxide, the fragrance piperonal via isosafrole, and the empathogenic/entactogenic...
often sold in preparations that also contain the synthetic chemical piperonylbutoxide, which enhances the toxicity to insects and is faster acting compared...
paralyzing the organism. Pyrethroids can be combined with the synergist piperonylbutoxide, a known inhibitor of microsomal P450 enzymes which are important...
synergically with certain insecticides like pyrethrins similarly to piperonylbutoxide, which likely results from inhibition of the MFO enzyme of insects...
found inhibitors of cytochrome P450, such as cobaltous chloride or piperonylbutoxide, blocked toxicity. Such testing has not been expanded to humans, however...
and drugs and chemicals such as tadalafil, MDMA, paroxetine and piperonylbutoxide. Enzymes within the cytochrome P450 superfamily are able to form methylenedioxy...
additive used to prevent pyrethroid from oxidizing during burning. Piperonylbutoxide (PBO): an optional additive to improve the effectiveness of pyrethroid...
for PiperonylButoxide" (PDF). USEPA. Wang J, Lu J, Mook RA, Zhang M, Zhao S, Barak LS, et al. (August 2012). "The insecticide synergist piperonyl butoxide...
and Elimite. An alternative is the combination of pyrethrins and piperonylbutoxide, in a topical application, which include the brands Licide, and A-200...
or their syntheses, such as the insecticide synergistic compound piperonylbutoxide. These plants are primarily harvested for commercial purposes in Asia...
needed in Asia and Latin America. In areas of high malaria resistance, piperonylbutoxide (PBO) combined with pyrethroids in mosquito netting is effective in...
treatment of head lice include lindane, malathion, carbaryl, pyrethrum, piperonylbutoxide, permethrin, phenothrin, bioallethrin, and spinosad. Many of the pediculicides...
usually performed on animals. Examples of pesticide synergists include Piperonylbutoxide and MGK 264. Human synergy relates to human interaction and teamwork...
action of insecticides ineffectual, even when co-administered with piperonylbutoxide. Characterization of the different forms of resistance among mosquitoes...
are insecticides derived from chrysanthemum flowers (pyrethrum). Piperonylbutoxide and n-octyl bicycloheptene dicarboximide often are added to pyrethrin...
US-GAAP Lead(II) oxide (PbO) Zylon, or Polybenzobisoxazole, a polymer Piperonylbutoxide, a pesticide synergist Peterborough railway station (National Rail...
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