A proteolipid is a protein covalently linked to lipid molecules, which can be fatty acids, isoprenoids or sterols. The process of such a linkage is known as protein lipidation, and falls into the wider category of acylation and post-translational modification. Proteolipids are abundant in brain tissue, and are also present in many other animal and plant tissues. They include ghrelin, a peptide hormone associated with feeding. Many proteolipids are composed of proteins covalenently bound to fatty acid chains,[1] often granting them an interface for interacting with biological membranes.[2] They are not to be confused with lipoproteins, a kind of spherical assembly made up of many molecules of lipids and some apolipoproteins.
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A proteolipid is a protein covalently linked to lipid molecules, which can be fatty acids, isoprenoids or sterols. The process of such a linkage is known...
Proteolipid protein 1 (PLP1) is a form of myelin proteolipid protein (PLP). Mutations in PLP1 are associated with Pelizaeus–Merzbacher disease. It is a...
enzymes Phantom limb pain, pain felt as from a missing limb Proteolipid protein 1 or proteolipid protein 2, associated with Pelizaeus-Merzbacher disease Pyridoxal...
Myelin proteolipid protein (PLP or lipophilin) is the major myelin protein from the central nervous system (CNS). It plays an important role in the formation...
oligodendrocyte glycoprotein (MOG), which is specific to the CNS; and proteolipid protein (PLP), which is the most abundant protein in CNS myelin, but...
Proteolipid protein 2 is a protein that in humans is encoded by the PLP2 gene. GRCh38: Ensembl release 89: ENSG00000102007 – Ensembl, May 2017 GRCm38:...
synthases. Subunit C (also called subunit 9, or proteolipid in F-ATPases, or the 16 kDa proteolipid in V-ATPases) was found in the Fo or Vo complex of...
trafficking in endothelial cells. The encoded protein, a member of the MAL proteolipid family, predominantly localizes in glycolipid- and cholesterol-enriched...
such as myelin oligodendrocyte glycoprotein, myelin basic protein, and proteolipid protein, causing an autoimmune response. This sets off a cascade of signaling...
is different in the two types. In the CNS the major myelin protein is proteolipid protein, and in the PNS it is myelin basic protein. Nodes of Ranvier...
encoding protein Placenta-specific protein 1 PLP2: encoding protein Proteolipid protein 2 PRR32: encoding protein PRR32 RPA4: encoding protein Replication...
neurobiology and biochemistry. She was the first to identify the Folch-Lees proteolipid. She served as president of the American Society for Neurochemistry in...
are misconstrued protein islands, which they propose form through a proteolipid code. Nonetheless, it has been proposed that they are specialized membrane...
3-position by the enzyme ghrelin O-acyltransferase (GOAT) to form a proteolipid. It is located on the cell membrane of ghrelin cells in the stomach and...
lipoproteins, since they are formed by lipids and proteins. Some transmembrane proteolipids, especially those found in bacteria, are referred to as lipoproteins;...
V-type proton ATPase 21 kDa proteolipid subunit is an enzyme that in humans is encoded by the ATP6V0B gene. This gene encodes a component of vacuolar...
and 40%. Myelin basic protein has been shown to interact in vivo with proteolipid protein 1, and in vitro with calmodulin, actin, tropomyosin, tubulin...
from the paternal allele in normal adults. The protein neuronatin, a proteolipid, that functions in the control of ion channels during brain development...
by Ca2+, the membrane fusion of vesicles form water-filled pores from proteolipids. Pore forming cytolysins such as perforin are used in cytotoxic killer...
V-type proton ATPase 16 kDa proteolipid subunit is an enzyme that in humans is encoded by the ATP6V0C gene. This gene encodes a component of vacuolar...
sequence (His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe) (PLP (proteolipid protein) 139-151 epitope) with that of a human myelin-specific epitope...
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