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Prostaglandin E information


Prostaglandin E
PGE1 (alprostadil) - top
PGE2 (dinoprostone) - bottom
Clinical data
ATC code
  • G02AD (WHO)
Identifiers
CAS Number
  • 11042-70-9
ChemSpider
  • none

Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications.

Types include:

  • Prostaglandin E1 also known as alprostadil
  • Prostaglandin E2 also known as dinoprostone

Both types are on the World Health Organization's List of Essential Medicines.[1]

Prostaglandin E play an important role in thermoregulation of the human brain. Decreased formation of prostaglandin E through inhibition of cyclooxygenase is the basis for the antipyretic of nonsteroidal anti-inflammatory drugs (NSAIDs).

  1. ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.

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