PGE1 (alprostadil) - top PGE2 (dinoprostone) - bottom
Clinical data
ATC code
G02AD (WHO)
Identifiers
CAS Number
11042-70-9
ChemSpider
none
Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications.
Types include:
Prostaglandin E1 also known as alprostadil
Prostaglandin E2 also known as dinoprostone
Both types are on the World Health Organization's List of Essential Medicines.[1]
Prostaglandin E play an important role in thermoregulation of the human brain. Decreased formation of prostaglandin E through inhibition of cyclooxygenase is the basis for the antipyretic of nonsteroidal anti-inflammatory drugs (NSAIDs).
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
Prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids that have diverse hormone-like effects in animals. Prostaglandins...
ProstaglandinE is a family of naturally occurring prostaglandins that are used as medications. Types include: Prostaglandin E1 also known as alprostadil...
Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. Dinoprostone...
generates prostaglandinE (PGE) from prostaglandin H2. The synthase generating PGE2 is a membrane-associated protein. Humans express three prostaglandin-E synthase...
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
Prostaglandin H2 (PGH2), or prostaglandin H2 (PGH2), is a type of prostaglandin and a precursor for many other biologically significant molecules. It...
Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
Prostaglandin EP3 receptor (EP3, 53kDa), is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; it is one of four identified...
Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
The prostaglandin E2 (PGE2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin E2. They are members of the prostaglandin...
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
Prostaglandin E2 receptor 1 (EP1) is a 42kDa prostaglandin receptor encoded by the PTGER1 gene. EP1 is one of four identified EP receptors, EP1, EP2, EP3...
Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans; it is one of four identified...
Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of...
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
Prostaglandin G2 is an organic peroxide belonging to the family of prostaglandins. The compound has been isolated as a solid, although it is usually used...
Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP1), as well as CRTH2 (DP2). It is a major prostaglandin produced by...
Energetyczna Portland General Electric PGE Park Propylene glycol ether ProstaglandinE Provisional Government of Eritrea This disambiguation page lists articles...
administered intravenously to horses. A single dose has been shown to reduce prostaglandin E2 production and inflammatory exudate for up to 15 hours, although...
or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, (i.e. PGD2), PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2)...
ω-6) with elongation and unsaturation. AA is the precursor to some prostaglandins, leukotrienes (LTA, LTB, LTC), thromboxane (TXA) and the N-acylethanolamine...
in animal fats. It is a precursor in the formation of leukotrienes, prostaglandins, and thromboxanes. Together with omega-3 fatty acids and other omega-6...
present. PGE2 acts on neurons in the preoptic area (POA) through the prostaglandinE receptor 3 (EP3). EP3-expressing neurons in the POA innervate the dorsomedial...
response. Prostanoids are a subclass of eicosanoids consisting of the prostaglandins (mediators of inflammatory and anaphylactic reactions), the thromboxanes...
breastfeeding. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. In 2021, diclofenac was the 61st most...