Predisease state of hyperglycemia with high risk for diabetes
Medical condition
Prediabetes
White hexagons in the image represent glucose molecules, which are increased in the lower image. Hyperglycemia is the only major sign of prediabetes.
Specialty
Endocrinology
Complications
Diabetic complications
Prediabetes is a component of metabolic syndrome and is characterized by elevated blood sugar levels that fall below the threshold to diagnose diabetes mellitus. It usually does not cause symptoms but people with prediabetes often have obesity (especially abdominal or visceral obesity), dyslipidemia with high triglycerides and/or low HDL cholesterol, and hypertension.[1] It is also associated with increased risk for cardiovascular disease (CVD). Prediabetes is more accurately considered an early stage of diabetes as health complications associated with type 2 diabetes often occur before the diagnosis of diabetes.
Prediabetes can be diagnosed by measuring hemoglobin A1c, fasting glucose, or glucose tolerance test. Many people may be diagnosed through routine screening tests. The primary treatment approach includes lifestyle changes such as exercise and dietary adjustments. Some medications can be used to reduce the risks associated with prediabetes. There is a high rate of progression to type 2 diabetes but not everyone with prediabetes develops type 2 diabetes.[2] Prediabetes can be a reversible condition with lifestyle changes.
For many people, prediabetes and diabetes are diagnosed through a routine screening at a check-up. The earlier prediabetes is diagnosed, the more likely an intervention will be successful.
^American Diabetes Association (January 2017). "2. Classification and Diagnosis of Diabetes". Diabetes Care. 40 (Suppl 1): S11–S24. doi:10.2337/dc17-S005. PMID 27979889.
^Bennasar-Veny M, Fresneda S, López-González A, Busquets-Cortés C, Aguiló A, Yañez AM (May 2020). "Lifestyle and Progression to Type 2 Diabetes in a Cohort of Workers with Prediabetes". Nutrients. 12 (5): 1538. doi:10.3390/nu12051538. PMC 7284825. PMID 32466178.
with prediabetes. There is a high rate of progression to type 2 diabetes but not everyone with prediabetes develops type 2 diabetes. Prediabetes can be...
48% between 2017 and 2045. As of 2020, 38% of all US adults had prediabetes. Prediabetes is an early stage of diabetes. Diabetes was one of the first diseases...
medication or insulin symptoms can be improved. type 1 and type 2 diabetes or prediabetes. If diagnosed with diabetes, regular glucose tests can help manage or...
racial and ethnic minorities. Insulin resistance, metabolic syndrome, and prediabetes are closely related to one another and have overlapping aspects. The...
Microalbuminuria is an important adverse predictor of glycemic outcomes in prediabetes. Prediabetes individuals with increased microalbuminuria even in the so-called...
after fasting, although not so high as to signal diabetes. A type of prediabetes. Impaired glucose tolerance (IGT) Blood sugar levels too high after a...
prediabetes in that an abnormal response to Orinase following administration of cortisone in a "stress test" could be taken to indicate prediabetes....
diabetes and prediabetes, in combination with physical exercise and a weight loss goal of 5-15% for diabetes and 7-10% for prediabetes to prevent progression...
Impaired fasting glucose is a type of prediabetes, in which a person's blood sugar levels during fasting are consistently above the normal range, but...
symptoms...in the prediabetes group", and stated that "A search for alternate neuropathy causes is needed in patients with prediabetes." The treatment of...
the blood; a high fasting glucose blood sugar level may be a sign of prediabetes or diabetes mellitus. The glycemic index is an indicator of the speed...
drug used to treat diabetes mellitus type 2 and, in some countries, prediabetes. It is a generic sold in Europe and China as Glucobay (Bayer AG), in...
"Effect of Fenugreek on Hyperglycaemia and Hyperlipidemia in Diabetes and Prediabetes: a Meta-analysis". Journal of Ethnopharmacology. 194: 260–268. doi:10...
Gynecomastia Heart disease Hypertension Obesity and cancer Osteoarthritis Prediabetes Sleep apnea Type 2 diabetes Management of obesity Anti-obesity medication...
Fasting levels between 5.6 and 6.9 mmol/L (100 and 125 mg/dL) indicate prediabetes ("impaired fasting glucose"), and fasting levels repeatedly at or above...
Gynecomastia Heart disease Hypertension Obesity and cancer Osteoarthritis Prediabetes Sleep apnea Type 2 diabetes Management of obesity Anti-obesity medication...
and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic...
decrease in risk of type 2 diabetes, combined type 2 diabetes and prediabetes, and prediabetes. A 2011 Cochrane systematic review examined one study that showed...
Gynecomastia Heart disease Hypertension Obesity and cancer Osteoarthritis Prediabetes Sleep apnea Type 2 diabetes Management of obesity Anti-obesity medication...
Archived from the original on 5 August 2007. "Diagnosis of Diabetes and Prediabetes". National Institute of Diabetes and Digestive and Kidney Diseases. June...
mission includes serving the 11 million Canadians living with diabetes or prediabetes. Diabetes Canada programs include: Its programs, education and services...
doi:10.2337/dc19-S005. PMID 30559231. "8 eating plans for patients with prediabetes". American Medical Association. 25 December 2019. Retrieved 4 October...
2019 consensus report on nutrition therapy for adults with diabetes and prediabetes the American Diabetes Association (ADA) states "Reducing overall carbohydrate...
Gynecomastia Heart disease Hypertension Obesity and cancer Osteoarthritis Prediabetes Sleep apnea Type 2 diabetes Management of obesity Anti-obesity medication...
nutritional value. It is safe to consume for individuals with diabetes or prediabetes. People with sulfonamide allergies can experience allergic reactions...
Predisease Predisease is a subclinical or prodromal vanguard of a disease. Prediabetes and prehypertension are common examples. The nosology or epistemology...
1161/CIRCULATIONAHA.108.772822. PMC 2777731. PMID 18606913. "Why your patients with prediabetes might benefit from interval training". American Medical Association....
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