Praziquantel (PZQ), sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections in mammals, birds, amphibians, reptiles, and fish.[3] In humans specifically, it is used to treat schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, echinococcosis, paragonimiasis, fasciolopsiasis, and fasciolosis.[3] It should not be used for worm infections of the eye.[4] It is taken by mouth.[3]
Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions.[4] While it may be used during pregnancy, it is not recommended for use during breastfeeding.[4] Praziquantel is in the anthelmintic class of medications.[3] It works partly by affecting the function of the worm's sucker.[3]
Praziquantel was approved for medical use in the United States in 1982.[3] It is on the World Health Organization's List of Essential Medicines.[5]
^"Product monograph brand safety updates". Health Canada. February 2024. Retrieved 24 March 2024.
^"Farnam Pet Press Release. TRUSTED D-WORM offers product for tapeworm management". Farnam Companies, Inc. Archived from the original on 14 October 2008. Retrieved 3 October 2016.
^ abcdef"Praziquantel". The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.
^ abcWorld Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 88, 593. hdl:10665/44053. ISBN 9789241547659.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
Praziquantel (PZQ), sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections in mammals...
number of snails. In areas where the disease is common, the medication praziquantel may be given once a year to the entire group. This is done to decrease...
metabolite of another anthelmintic drug, febantel. Ivermectin Nocodazole Praziquantel "Fenbendazole: From MD Anderson to Joe Tippens". Institute of Integrative...
sleeping The prescription drug Praziquantel is usually prescribed in a single dose to patients infected with H.nana. Praziquantel is widely used and preferred...
mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Many early treatments were herbal, such as the oil of herbs of the genus...
Prevention is by properly cooking meat. Treatment is generally with praziquantel, though niclosamide may also be used. Together with cysticercosis, infections...
deworm at least 1–2 times per year with ivermectin + praziquantel or moxidectin + praziquantel to target tapeworms, bots, and small strongyles. This...
Treatment of those with neurocysticercosis may be with the medications praziquantel or albendazole. These may be required for long periods. Steroids, for...
topical formulation containing fipronil, (S)-methoprene, eprinomectin and praziquantel was shown to be efficient for the prevention of Otodectes cynotis infestation...
medication used to treat schistosomiasis due to Schistosoma mansoni. Praziquantel, however, is often the preferred treatment. It is given by mouth and...
other helminthes infections. The therapy of choice is praziquantel, a quinolone derivative. Praziquantel is generally administered in an oral form in one or...
LJ, Tan MY (March 1999). "Improvement of the in vitro dissolution of praziquantel by complexation with α-, β- and γ-cyclodextrins". International Journal...
Arpraziquantel ((R)-praziquantel) is the eutomer (the biologically active enantiomer) of praziquantel, a medication which is under investigation for the...
will have significant improvement in seizure control. A combination of praziquantel and albendazole is more effective in treating neurocystercosis. A 2014...
Praziquantel (while not approved for use in ruminants in the US) is also 99–100% effective while albendazole is 19-75% effective; and praziquantel +...
can be used both preventatively and to treat infections. For example, praziquantel is an effective treatment for tapeworm infection, and is preferred over...
were the major animal species affected by trypanosomosis. Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection...
paucibacillary leprosy comprises ofloxacin, rifampicin, and minocycline. Praziquantel can be useful for treating infections caused by all Schistosoma species...
perstans infection. Praziquantel is effective against various helminthic and protozoan infections. The few studies about the use of praziquantel against M. perstans...
neurocysticercosis includes epileptic therapy and a long-course medication of praziquantel (PZQ) and/or albendazole. Steroid therapy may be necessary to minimize...
medicine taken by mouth. The most commonly used medicine for tapeworms is praziquantel. "Intestinal worms". World Health Organization. Archived from the original...
anti-schistosomal drug from 1919 on. It was subsequently replaced by praziquantel. Antimony and its compounds are used in several veterinary preparations...
also be useful in the treatment of paragonimiasis and dicrocoeliasis. Praziquantel is effective in the treatment of all diseases caused by flukes (clonorchiasis...
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