Mansonella perstans is a filarial (arthropod-borne) nematode (roundworm), transmitted by tiny blood-sucking flies called midges.[1]Mansonella perstans is one of two filarial nematodes that causes serous cavity filariasis in humans. The other filarial nematode is Mansonella ozzardi. M. perstans is widespread in many parts of sub-Saharan Africa, parts of Central and South America, and the Caribbean.[1][2]
Compared to infections with other filarial parasites such as Wuchereria bancrofti, Brugia malayi, and Loa loa, Mansonella infections are relatively mild. However, the pathogenicity of M. perstans infection has been recently reconsidered in various studies.[3] These studies have demonstrated that M. perstans has the ability to induce a variety of clinical features, including angioedema Calabar-like swellings, pruritus, fever, headache, eosinophilia, and abdominal pain. The overall disability among populations in regions where filariae are endemic has been difficult to determine because of high rates of coinfection with other filariae and the nonspecificity of M. perstan infections. Furthermore, treatment of M. perstans is challenging because the most antifilarial drugs, such as ivermectin, diethylcarbamazine, and albendazole are not effective. The optimal treatment for M. perstans infection remains unclear.[3] Most current studies are focused on coinfection of M. perstans with other filarial parasites, and the study of Wolbachia bacteria as endosymbionts in M. perstans and other filarial parasites.
^"Mansonelliasis—perstans". GIDEON: The Global Infectious Disease & Epidemiology Network. 2010.
^ abBregani ER, Rovellini A, Mbaïdoum N, Magnini MG (May 2006). "Comparison of different anthelminthic drug regimens against Mansonella perstans filariasis". Transactions of the Royal Society of Tropical Medicine and Hygiene. 100 (5): 458–63. doi:10.1016/j.trstmh.2005.07.009. PMID 16257021.
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Mansonellaperstans is a filarial (arthropod-borne) nematode (roundworm), transmitted by tiny blood-sucking flies called midges. Mansonellaperstans is...
ozzardi, M. perstans, and M. streptocerca. There are nine species: Mansonella barbascalensis Mansonella llewellyni Price, 1962 Mansonella longicapitata...
humans. The other filarial nematode that causes it in humans is Mansonellaperstans. M. ozzardi is an endoparasite that inhabits the serous cavity of...
host cells. Some human parasites, e.g. Wuchereria bancrofti and Mansonellaperstans, thrive in their intermediate insect hosts because of an obligate...
blindness. Serous cavity filariasis is caused by the worms Mansonellaperstans and Mansonella ozzardi, which occupy the serous cavity of the abdomen. Dirofilaria...
Agbolade, O.M.; Akinboye, D.O.; Ogunkola, O. (2005). "Loa loa and Mansonellaperstans: neglected human infections that need control in Nigeria". Afr. J...
midges or blackflies. It is usually asymptomatic. Infections by Mansonellaperstans, while often asymptomatic, can be associated with angioedema, pruritus...
infection. The first investigation focussed on Filaria perstans (later renamed Mansonellaperstans), a small roundworm transmitted by flies, and bacteria...
less seriously pathogenic but commonly parasitise humans. Mansonella ozzardi Mansonellaperstans Some Dirofilaria species usually parasitize animals such...
transmission and lethality) Hepatitis D Hookworm-malaria coinfection Mansonellaperstans Trichuriasis Chikungunya and Dengue coinfection Dengue and HIV coinfection...
filariasis) Loa loa Mansonella (see also mansonelliasis) Mansonella ozzardi (parasite of man in Central and South America) Mansonellaperstans (parasite of humans...
Spiruria Microfilariae of Mansonellaperstans (left) and Loa loa (Spirurida: Filariidae) Scientific classification Domain: Eukaryota Kingdom: Animalia...
treatment. Acanthocheilonemiasis is caused by the parasite, mansonellaperstans. M. perstans is primarily found in central Africa and in some areas of South...
first Commission. He was assigned to look for Filaria perstans (later renamed Mansonellaperstans), a small roundworm transmitted by flies, as a possible...
to be vectors for the following viruses and conditions: Mansonella spp. (M. ozzardi, M. perstans, M. streptocerca), Onchocerca gibsoni and O. cervicalis...
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