It has been suggested that this article should be split into articles titled Asymptomatic hyperleukocytosis and symptomatic hyperleukocytosis. (discuss) (September 2020)
Leukostasis (also called symptomatic hyperleukocytosis) is a medical emergency most commonly seen in patients with acute myeloid leukemia. It is characterized by an extremely elevated blast cell count and symptoms of decreased tissue perfusion. The pathophysiology of leukostasis is not well understood, but inadequate delivery of oxygen to the body's cells is the result. Leukostasis is diagnosed when white cell plugs are seen in the microvasculature. The most common symptoms are dyspnea and hypoxia, usually accompanied by visual changes, headaches, dizziness, confusion, somnolence, and coma. Prompt treatment is required since, if left untreated, it has a very high mortality rate. Treatments aim to rapidly reduce white blood cell counts while also treating the underlying disorder.
pathophysiology of leukostasis is not well understood, but inadequate delivery of oxygen to the body's cells is the result. Leukostasis is diagnosed when...
form of leukocytosis, in which the WBC count exceeds 100,000/µL, is leukostasis. In this form there are so many WBCs that clumps of them block blood...
HUS, or diarrhea-associated HUS IV Leukocytosis Leukostasis Leukapheresis I Prophylaxis of leukostasis III Hyperviscosity in monoclonal gammopathy Treatment...
chronic leukemias, white blood cell counts may be high enough to cause leukostasis and "sludging" in the capillaries (acute leukemias have a more variable...
leukemia cutis (i.e. skin nodules caused by leukemic infiltrates), or leukostasis (i.e. an emergency situation in which excessive elevations in circulating...
intercellular adhesion molecule-1 mRNA and protein levels and therefore reduce leukostasis and help maintain the blood-retinal-barrier. Its potency is 5 times greater...
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