Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Pivalic acid is a carboxylic acid with a molecular formula of (CH3)3CCO2H. This colourless, odiferous organic compound is solid at room temperature. Two abbreviations for pivalic acid are t-BuC(O)OH and PivOH. The pivalyl or pivaloyl group is abbreviated t-BuC(O).
Pivalic acid is an isomer of valeric acid, the other two isomers of it are 2-Methylbutanoic acid and 3-Methylbutanoic acid.
Pivalicacid is a carboxylic acid with a molecular formula of (CH3)3CCO2H. This colourless, odiferous organic compound is solid at room temperature. Two...
chloride. It was first made by Aleksandr Butlerov in 1874 by reacting pivalicacid with phosphorus pentachloride. Pivaloyl chloride is used as an input...
isobutylene to pivalicacid. In the Koch reaction, the addition of water and carbon monoxide to alkenes or alkynes is catalyzed by strong acids. Hydrocarboxylations...
Lindstedt S, Nordin I (June 1995). "Effect of short-term treatment with pivalicacid containing antibiotics on serum carnitine concentration—a risk irrespective...
valeric acid in Wiktionary, the free dictionary. List of saturated fatty acids List of carboxylic acids 4-Hydroxy-4-methylpentanoic acidPivalicacid (2,2-dimethylpropanoic...
produced Koch acids include pivalicacid, 2,2-dimethylbutyric acid and 2,2-dimethylpentanoic acid. When standard acid catalysts such as sulfuric acid or a mix...
Carboxylic acids are organic acids characterized by a carboxyl (-COOH) functional group. The naming of these compounds is governed by IUPAC nomenclature...
be acidic to ensure protonation of said heterocycle. A typical reaction is that between pyridine and pivalicacid with silver nitrate, sulfuric acid and...
colorless liquid, the methyl ester of pivalicacid. The ester is well known for being resistant to hydrolysis to the parent acid. Hydrolysis can be effected with...
structures after he independently synthesised the compound trimethylacetic (pivalic) acid which Friedel had obtained earlier by oxidizing with a dichromate. Some...
lipophilicity compared to that of ampicillin. Prodrugs that release pivalicacid when broken down by the body—such as pivampicillin, pivmecillinam, and...
(1981). "The temperature dependence of positron lifetimes in solid pivalicacid". Chemical Physics. 63 (1–2): 51. Bibcode:1981CP.....63...51E. doi:10...
HOCH2}}{\color {red}{\ce {CO}}}{\ce {OH}}} The conversion of isobutene to pivalicacid is also illustrative: Me 2 C = CH 2 + H 2 O + CO ⟶ Me 3 C CO OH {\displaystyle...
acetate, bis(diphenylphosphino)methane (dppm) and the caesium salt of pivalicacid (CsPiv) Pd-Catalyzed Alkyl to Aryl Migration and Cyclization: An Efficient...
upon reacting pyridine with pivalicacid, silver nitrate and ammonium in sulfuric acid with a yield of 97%. Lewis acids easily add to the nitrogen atom...
pivoxil. Tenofovir disoproxil contains a very similar prodrug group. Pivalicacid Wuts, P. G. M.; Greene, T.W. (2006). Greene's Protective Groups in Organic...
Imaki K, Arai Y, Okegawa T, "Derivatives of p-substituted phenyl ester of pivalicacid", issued 21 May 1991, assigned to Ono Pharmaceutical Co Ltd v t e...
the Prins reaction. It also is generated by ketonization of pivalicacid and acetic acid or acetone over metal oxide catalysts. 3-Methylbutanal is a starting...
"Palladium-catalyzed benzene arylation: incorporation of catalytic pivalicacid as a proton shuttle and a key element in catalyst design". J. Am. Chem...
treatment of otitis externa and otomycosis. It is usually formulated as the pivalicacid ester prodrug called flumetasone pivalate. In April 2023, the US Food...
tert-butyl group having the chemical formula: tBu-CO-NH2. It is the amide of pivalicacid. N-Pivalamide, is a functional group having the following chemical formula:...
estrogen medication and an estrogen ester; specifically, a pivalicacid (trimethylacetic acid) ester of estradiol. Literature sources are conflicting as...
2-Hydroxyalkanoates Using the Enantioselective Mixed-Anhydride Method with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst". Chem. Eur. J. 16 (1): 167–172...