Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Methyl pivalate is an organic compound with the formula CH3O2CC(CH3)3. It is a colorless liquid, the methyl ester of pivalic acid. The ester is well known for being resistant to hydrolysis to the parent acid. Hydrolysis can be effected with a solution of trimethylsilyl iodide in hot acetonitrile followed by aqueous workup.[1][2]
^Olah, George A.; Narang, Subhash C.; Gupta, B. G. Balaram; Malhotra, Ripudaman (1979). "Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ Iodotrimethylsilane Reagent". J. Org. Chem. 44: 1247–1251. doi:10.1021/jo01322a012.
Methylpivalate is an organic compound with the formula CH3O2CC(CH3)3. It is a colorless liquid, the methyl ester of pivalic acid. The ester is well known...
deprotection methods involve hydrolysis with a base or other nucleophiles. Methylpivalate Kubitschke, Jens; Lange, Horst; Strutz, Heinz (2014). "Carboxylic Acids...
Deoxycorticosterone pivalate (DOCP), also known as desoxycorticosterone trimethyl acetate (DOC-TMA or DCT) and sold under the brand names Zycortal, Percorten...
Tixocortol pivalate is a corticosteroid. It has anti-inflammatory properties similar to hydrocortisone. It is marketed under the brand name Pivalone. It...
Clocortolone pivalate (brand names Cilder, Cloderm, Purantix), also known as clocortolone trimethylacetate, is a synthetic glucocorticoid corticosteroid...
decongestant. Tixocortol pivalate Larochelle P, Du Souich P, Bolte E, Lelorier J, Goyer R (March 1983). "Tixocortol pivalate, a corticosteroid with no...
Flumetasone pivalate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of flumetasone. A Sayed R, Mohamed...
is a topical steroid. It is used in the form of an ester, clocortolone pivalate, and applied as a cream. It is used for the treatment of dermatitis and...
Estradiol pivalate, also known as estradiol trimethyl acetate (E2-TMA) and sold under the brand name Estrotate, is an estrogen medication and an estrogen...
and methanol. Methylprednisolone acetate suspension (Depo-Medrol) is a 6-methyl derivative of prednisolone that melts at 215 degrees Celsius with some decomposition...
1(2)-dehydrogenation, 6α-, 9α-, 16α-, and 16β-substitution (with a halogen or methyl group), 16α,17α-acetonidation, and 17α- and 21-esterification. 11-Dehydrocorticosterone...
dexamethasone, the two compounds differing only in the spatial configuration of the methyl group at position 16 (see steroid nomenclature). Betamethasone was patented...
acetate, and is the analogue of methenmadinone acetate without the C19 methyl group or the C6 double bond. A derivative of SGA with even greater progestogenic...
(DHT). Metribolone, also known as 17α-methyltrenbolone, as well as 17α-methyl-δ9,11-19-nortestosterone or 17α-methylestra-4,9,11-trien-17β-ol-3-one, is...
chemically as 6α-methyl-17α-acetoxyprogesterone or as 6α-methyl-17α-acetoxypregn-4-ene-3,20-dione, and its generic name is a contraction of 6α-methyl-17α-hydroxyprogesterone...
esters with common protecting-group use are the acetate, benzoate, and pivalate esters, for these exhibit differential removal. Sterically hindered esters...
usually formulated as the pivalic acid ester prodrug called flumetasone pivalate. In April 2023, the US Food and Drug Administration approved the first...
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