Nociception assay information

A nociception assay (nocioception or nocioperception assay) evaluates the ability of an animal, usually a rodent, to detect a noxious stimulus such as...

numerous definitions of pain, almost all involve two key components. First, nociception is required. This is the ability to detect noxious stimuli which evokes...

does not have pore-forming activity. In mice, Ts8 increases earlier nociception with higher doses. Elimination or inhibition of Kv4.2 channels via intraplantar...

dendritic arborisation, respiratory rhythm, neurotoxicity, pain, and nociception. In 2014, it was found that substance P played a role in male fruit fly...

receptors, which target a variety of peripheral terminals involved in nociception. Signals on this track are also transmitted to the periaqueductal gray...

has been implicated in many biologically diverse functions, including: nociception, waking and sleep regulation, cognition, feeding, regulation of mood...

mechanical stimulation of the cuticle and sound detection) and cold nociception. TRPP, P for "polycistin", is named for polycystic kidney disease, which...

sub-population of peripheral C-fibers is considered important sensors of nociception in humans and their activation will under normal conditions give rise...

"Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception". Prostaglandins Other Lipid Mediat. 96 (1–4): 76–83. doi:10.1016/j.prostaglandins...

TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception". Molecules. 20 (10): 18907–22. doi:10.3390/molecules201018907. PMC 6331789...

"Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception". Prostaglandins & Other Lipid Mediators. 96 (1–4): 76–83. doi:10.1016/j...

NT-3 or TrkC display severe sensory defects. These mice have normal nociception, but they are defective in proprioception, the sensory activity responsible...

and is largely found in small diameter axons such as those found in nociception neurons. When a significant level of TTX is ingested, it will bind sodium...

PMID 10353985. Immke DC, Gavva NR (October 2006). "The TRPV1 receptor and nociception". Seminars in Cell & Developmental Biology. 17 (5): 582–91. doi:10.1016/j...

a cellular target. One assay to determine the extent at which a ligand binds to its receptor is the radioligand binding assay (RBA), in which specific...

such as Alzheimer's disease. Studies suggest that FFAR1 is involved in nociception, i.e., the perception of pain. 1) Oral administration of the FFAR1 agonist...