How an organism receives and responds to painful stimuli
In physiology, nociception (/ˌnəʊsɪˈsɛpʃ(ə)n/), also nocioception; from Latin nocere 'to harm/hurt') is the sensory nervous system's process of encoding noxious stimuli. It deals with a series of events and processes required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal to trigger an appropriate defensive response.
In nociception, intense chemical (e.g., capsaicin present in chili pepper or cayenne pepper), mechanical (e.g., cutting, crushing), or thermal (heat and cold) stimulation of sensory neurons called nociceptors produces a signal that travels along a chain of nerve fibers via the spinal cord to the brain.[1] Nociception triggers a variety of physiological and behavioral responses to protect the organism against an aggression, and usually results in a subjective experience, or perception, of pain in sentient beings.[2]
^Portenoy, Russell K.; Brennan, Michael J. (1994). "Chronic Pain Management". In Good, David C.; Couch, James R. (eds.). Handbook of Neurorehabilitation. Informa Healthcare. ISBN 978-0-8247-8822-3. Archived from the original on 2020-10-24. Retrieved 2017-09-06.
^Bayne, Kathryn (2000). "Assessing Pain and Distress: A Veterinary Behaviorist's Perspective". Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings of the Workshop Held June 22, 2000. National Academies Press. pp. 13–21. ISBN 978-0-309-17128-1. Archived from the original on September 13, 2019. Retrieved May 17, 2020.
In physiology, nociception (/ˌnəʊsɪˈsɛpʃ(ə)n/), also nocioception; from Latin nocere 'to harm/hurt') is the sensory nervous system's process of encoding...
A nociception assay (nocioception or nocioperception assay) evaluates the ability of an animal, usually a rodent, to detect a noxious stimulus such as...
expressed by DRG sensory neurons and might play a role in acid-induced nociception. The nerve endings of dorsal root ganglion neurons have a variety of...
postherpetic neuralgia. Nociplastic pain is pain characterized by a changed nociception (but without evidence of real or threatened tissue damage, or without...
body part, so the threat can be mitigated; this process is called nociception. Nociception and pain are usually evoked only by pressures and temperatures...
cord and not involving the brain. Nociception is found, in one form or another, across all major animal taxa. Nociception can be observed using modern imaging...
flinching or withdrawal of a limb. Nociception is found, in one form or another, across all major animal taxa. Nociception can be observed using modern imaging...
responses to nociception can be detected, and no reference need be made to a conscious experience of pain. Based on such criteria, nociception has been observed...
the oldest examples is probably the Greeks' theory of beneception and nociception. They believed that these two principles decided the motivation in all...
Nicholas Wood FRS is a British neurobiologist, and Head of the Molecular Nociception Group, at University College London. He earned a Ph.D. in virology at...
numerous definitions of pain, almost all involve two key components. First, nociception is required. This is the ability to detect noxious stimuli which evokes...
anesthetic is a drug that causes reversible local anesthesia and a loss of nociception. When it is used on specific nerve pathways (nerve block), effects such...
article Nociception, nociception is the sensory nervous system's response to harmful stimuli, such as a toxic chemical applied to a tissue. In nociception, chemical...
temperature, mechanical stimuli (touch, pressure, stretch) or danger (nociception). Thus, different free nerve endings work as thermoreceptors, cutaneous...
temperature (thermoception), body position (proprioception), and pain (nociception). Somatosensation begins when mechano- and thermosensitive structures...
humans include spatial orientation, proprioception (body position) and nociception (pain). Further internal senses lead to signals such as hunger, thirst...
important in nociception, laminae III and IV are not involved nociception, and lamina V is involved in both nociception and non-nociception. Lamina I is...
a nervous system is essential for an animal to be able to experience nociception or pain. However, other physiological capacities are also required such...
anxiolysis or sedation rather than a failure of the block itself.: 1611 Nociception (pain sensation) is not hard-wired into the body. Instead, it is a dynamic...
An enkephalin is a pentapeptide involved in regulating nociception (pain sensation) in the body. The enkephalins are termed endogenous ligands, as they...
Mechanoreceptor – Sensory receptor cell responding to mechanical pressure or strain Nociception – How an organism receives and responds to painful stimuli Proprioception –...
flinching or withdrawal of a limb. Nociception is found, in one form or another, across all major animal taxa. Nociception can be observed using modern imaging...
brain areas that are important for controlling autonomic activity and nociception. Jeffrey D Blaustein (2006). Handbook of Neurochemistry and Molecular...
data such as tactition (pressure), thermoception (temperature), and nociception (pain) originating from the face above the jawline; it is also responsible...
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