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Dorsal root ganglion information


Dorsal root ganglion
A dorsal root ganglion (DRG) from a chicken embryo (around stage of day 7) after incubation overnight in NGF growth medium stained with anti-neurofilament antibody. Neurites growing out of the ganglion are visible.
A spinal nerve with its ventral and dorsal roots. The dorsal root ganglion is the "spinal ganglion", following the dorsal root.
Details
PrecursorNeural crest
Identifiers
Latinganglion sensorium nervi spinalis
MeSHD005727
TA98A14.2.00.006
TA26167
FMA5888
Anatomical terminology
[edit on Wikidata]

A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion[1]) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia.[2]

The axons of dorsal root ganglion neurons are known as afferents. In the peripheral nervous system, afferents refer to the axons that relay sensory information into the central nervous system (i.e. the brain and the spinal cord).

  1. ^ "Ganglion". Physiopedia. Retrieved 2021-05-15.
  2. ^ Purves, Dale; Augustine, George J.; Fitzpatrick, David; Katz, Lawrence C.; LaMantia, Anthony-Samuel; McNamara, James O.; Williams, S. Mark (2001). "The Major Afferent Pathway for Mechanosensory Information: The Dorsal Column-Medial Lemniscus System". Neuroscience. 2nd edition. Retrieved 30 May 2018.

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Dorsal root ganglion

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ganglion (pl.: ganglia) is a group of neuron cell bodies in the peripheral nervous system. In the somatic nervous system, this includes dorsal root ganglia...

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Pseudounipolar neuron

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is located within a dorsal root ganglion. The axon leaves the cell body (and out of the dorsal root ganglion) into the dorsal root, where it splits into...

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Sensory neuronopathy

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pain or ataxia) due to destruction of nerve cell bodies in the dorsal root ganglion. The causes of nerve damage are grouped into categories including...

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Afferent nerve fiber

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are aggregated in a swelling in the dorsal root known as the dorsal root ganglion. All of the axons in the dorsal root, which contains afferent nerve fibers...

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Spinal cord

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dividing cells along the dorsal ventral axis. Dorsal root ganglion neurons differentiate from neural crest progenitors. As the dorsal and ventral column cells...

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Intervertebral foramen

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spinal nerve and spinal blood vessels, and lodges a posterior (dorsal) root ganglion.: 425  Cervical, thoracic, and lumbar vertebrae all have intervertebral...

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in the treatment of pain. Procedures include neurectomy, cordotomy, dorsal root entry zone lesioning, and cingulotomy. Cutting through or removal of...

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The dorsal root or dorsal root ganglion (that carry mostly sensory signals) may be usefully targeted (called rhizotomy); with the dorsal root ganglion possibly...

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channels, from families with inherited erythromelalgia (IEM), make dorsal root ganglion (DRG, peripheral and sensory), neurons hyper excitable, thereby demonstrating...

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Tarlov cyst

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Tarlov cysts are defined as cysts formed within the nerve-root sheath at the dorsal root ganglion. The etiology of these cysts is not well understood; some...

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General visceral afferent fiber

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Finally, the signal continues along the dorsal root from the dorsal root ganglion to a region of gray matter in the dorsal horn of the spinal column where it...

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Spinothalamic tract

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cortex. Pseudounipolar neurons in the dorsal root ganglion have axons that lead from the skin into the dorsal spinal cord where they ascend or descend...

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Radicular artery

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anterior and posterior root of the spinal nerve and its sensory ganglion (dorsal root ganglion). At the level of the lumbosacral enlargement, a relatively...

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the ganglia adjacent to the spinal cord (called the dorsal root ganglion) or the trigeminal ganglion in the base of the skull. Shingles occurs only in people...

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Grey matter

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lie in the dorsal root ganglion. This information is then transmitted in axons up the spinal cord in spinal tracts, including the dorsal column-medial...

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TRPV1

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been shown to interact with: CALM1 SNAPAP SYT9 CBD AEA NPR1 PKG The dorsal root ganglion (DRG) neurons of mammals were known to express a heat-sensitive ion...

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phenomenon dorsal dorsal cochlear nucleus dorsal column dorsal column nuclei dorsal funiculus dorsal horn dorsal root dorsal root ganglion dorsal spinocerebellar...

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Cell type

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discovery of many new cell types in e.g. mouse cortex, hippocampus, dorsal root ganglion and spinal cord. Animals have evolved a greater diversity of cell...

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Platypus

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Ornithorhynchus anatinus, Induces a Calcium-Dependent Current in Cultured Dorsal Root Ganglion Cells". Journal of Neurophysiology. 85 (3): 1340–5. doi:10.1152/jn...

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Neurotrophic factors

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mechanism is still not known. Specifically, BDNF promotes survival of dorsal root ganglion neurons. Even when bound to a truncated TrkB, BDNF still shows growth...

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