Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Nverify (what is YN ?)
Infobox references
Chemical compound
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a Ca2+-mobilizing second messenger synthesised in response to extracellular stimuli. Like its mechanistic cousins, IP3 and cyclic adenosine diphosphoribose (Cyclic ADP-ribose), NAADP binds to and opens Ca2+ channels on intracellular organelles, thereby increasing the intracellular Ca2+ concentration which, in turn, modulates sundry cellular processes (see Calcium signalling). Structurally, it is a dinucleotide that only differs from the house-keeping enzyme cofactor, NADP by a hydroxyl group (replacing the nicotinamide amino group) and yet this minor modification converts it into the most potent Ca2+-mobilizing second messenger yet described. NAADP acts across phyla from plants to humans.
and 25 Related for: Nicotinic acid adenine dinucleotide phosphate information
Nicotinamide adeninedinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists...
component of the coenzymes nicotinamide adeninedinucleotide (NAD) and nicotinamide adeninedinucleotidephosphate (NADP+). Although niacin and nicotinamide...
by mouth) to prevent and treat pellagra (niacin deficiency). While nicotinicacid (niacin) may be used for this purpose, niacinamide has the benefit of...
calcium-releasing second messengers cyclic ADP-ribose (cADPR) and nicotinicacidadeninedinucleotidephosphate (NAADP). CD38 is most frequently found on plasma B cells...
Receptor Potential (TRP) channels, Cyclic nucleotide-gated (CNG) channels, Acid-sensing ion channels, and SOC channels. These channels can be regulated by...
component of the coenzymes nicotinamide adeninedinucleotide (NAD) and nicotinamide adeninedinucleotidephosphate (NADP+). Although niacin and nicotinamide...
Recent studies have cited the phospholipase A2 beta, nicotinicacidadeninedinucleotidephosphate (NAADP), and the protein STIM 1 as possible mediators...
cells. The ectoenzyme has been shown to be important in nicotinicacidadeninedinucleotidephosphate (NAADP) synthesis. NAADP is an intracellular second...
niacin. In humans, several enzymes use NMN to generate nicotinamide adeninedinucleotide (NADH). In mice, it has been proposed that NMN is absorbed via the...
biogenesis, exocytosis and autophagy. In bacterial infection nicotinicacidadeninedinucleotidephosphate (NAADP) induction of lysosomal Ca2+ efflux and TFEB...
release and globalisation of calcium signals, and that Nicotinicacidadeninedinucleotidephosphate (NAADP) is a ubiquitous trigger for initiating and co-ordinating...
reticulum of higher plants elicited by the NADP metabolite nicotinicacidadeninedinucleotidephosphate". Proceedings of the National Academy of Sciences. 97...
Nicotinate salvage is the process of regenerating nicotinamide adeninedinucleotide from nicotinicacid. This pathway is important for controlling the level of...
D-β-hydroxybutyric acid (hereafter termed β-hydroxybutyric acid), butyric acid, and niacin (also known as nicotinicacid). β-Hydroxybutyric and butyric acids are regarded...
binding-protein for the nucleotide second messenger, NAADP (nicotinicacidadeninedinucleotidephosphate) that activates endo-lysosomal Ca2+ channels TPCs (two-pore...
(−)-Limonene-3-hydroxylase (L3OH), using O2 and then nicotinamide adeninedinucleotidephosphate (NADPH) catalyzes the allylic hydroxylation of (−)-limonene...
nomenclature). Vitamin B13: orotic acid. Vitamin B14: cell proliferant, anti-anemia, rat growth factor, and antitumor pterin phosphate, named by Earl R. Norris...
pharmaceutical doses of the nicotinicacid are used under medical supervision as a treatment for hypercholesterolemia. High doses of nicotinicacid are also associated...
mitochondrial respiratory chain, leading to an accumulation of nicotinamide adeninedinucleotide hydrogen (NADH). Methylene blue acts as an alternative electron acceptor...
cyclic ADP-ribose (cADPR) by the CD38 enzyme using nicotinamide adeninedinucleotide (NAD+) as a cofactor. ADPR binds to and activates the TRPM2 ion channel...
glucose-6-phosphate dehydrogenase (Ki = 17 μM; IC50 = 18.7 μM), and is able to lower NADPHTooltip nicotinamide adeninedinucleotidephosphate levels and...
off-aromas in the resulting wine. Nicotinicacid – involved in the synthesis of Nicotinamide adeninedinucleotide (NAD+), a co-enzyme that is important...
Global Information
verify (what is 
?)
