Niclosamide, sold under the brand name Niclocide among others, is an anthelmintic medication used to treat tapeworm infestations, including diphyllobothriasis, hymenolepiasis, and taeniasis. It is not effective against other worms such as flukes or roundworms.[2] It is taken by mouth.[3]
Side effects include nausea, vomiting, abdominal pain, and itchiness. It may be used during pregnancy.[3] It works by blocking glucose uptake and oxidative phosphorylation by the worm.[4]
Niclosamide was first synthesized in 1958.[5] It is on the World Health Organization's List of Essential Medicines.[6] Niclosamide is not available for human use in the United States.[7]
^CID 4477 from PubChem
^"Niclosamide Advanced Patient Information - Drugs.com". www.drugs.com. Archived from the original on 20 December 2016. Retrieved 8 December 2016.
^ abWorld Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 81, 87, 591. hdl:10665/44053. ISBN 9789241547659.
^Lanusse CE, Alvarez LI, Sallovitz JM, Mottier ML, Sanchez Bruni SF (13 May 2013). "Antinematodal Drugs". In Riviere JE, Papich MG (eds.). Veterinary Pharmacology and Therapeutics. John Wiley & Sons. p. 1096. ISBN 978-1-118-68590-7. Archived from the original on 10 September 2017.
^Mehlhorn H (2008). Encyclopedia of Parasitology: A-M. Springer Science & Business Media. p. 483. ISBN 978-3-540-48994-8. Archived from the original on 2016-12-20.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^"Dipylidium - Resources for Health Professionals". U.S. Centers for Disease Control and Prevention (CDC). 21 May 2020.
Niclosamide, sold under the brand name Niclocide among others, is an anthelmintic medication used to treat tapeworm infestations, including diphyllobothriasis...
a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as...
Drug interactions may occur if salicylanilides such as dibromsalan and niclosamide are co-administered. Abortions in cattle and death in sheep have been...
properly cooking meat. Treatment is generally with praziquantel, though niclosamide may also be used. Together with cysticercosis, infections affect about...
non-toxic, most are approved for use in organic gardening Metaldehyde Niclosamide Acetylcholinesterase inhibitors (e.g. methiocarb), highly toxic to other...
acts by uncoupling of oxidative phosphorylation in flukes. Along with niclosamide, another tapeworm drug, it has been recently found to display "strong...
diphyllobothriasis. Niclosamide An alternative treatment is niclosamide, 2 g orally once for adults or 50 mg/kg (max 2 g) for children. Niclosamide is not available...
timori, and Loa loa Salicylanilide – mitochondrial un-couplers such as Niclosamide and Oxyclozanide, and are used only for flatworm infections Nitazoxanide...
easily treated with praziquantel (5–10 mg/kg, single-administration) or niclosamide (adults and children over 6 years: 2 g, single-administration after a...
species of fish. Examples of piscicides include rotenone, saponins, TFM, niclosamide and Antimycin A (Fintrol). Historically, fishing techniques of indigenous...
should be offered B12 supplementation along with anti-parasitics such as niclosamide or praziquantel. List of parasites (human) Muratov, IV; Posokhov, PS...
diarrhea Examination of the stool for eggs and parasites Praziquantel, niclosamide No Epstein–Barr virus (EBV) Epstein–Barr virus infectious mononucleosis...
effective treatment for tapeworm infection, and is preferred over the older niclosamide. While accidental tapeworm infections in developed countries are quite...
H (1987). "Treatment of fish parasites. 2. Effects of praziquantel, niclosamide, levamisole-HCl, and metrifonate on monogenea (Gyrodactylus aculeati...
Cestoda. Examples include: albendazole albendazole sulfoxide dichlorophen niclosamide quinacrine Anticestodal+agents at the U.S. National Library of Medicine...
neurological condition, the boy was treated with niclosamide rather than praziquantel. In this case, niclosamide treatment proved to be successful. Wikimedia...
infections, the drugs of choice to kill adult tapeworms are praziquantel or niclosamide. Pets can be prevented from becoming infested with tapeworm if they are...
then use one of these drugs: Epsiprantel, Praziquantel, Mebendazole, Niclosamide, Bunamindine hydrochloride or Fenbendazole. This will kill the adult...
Opisthorchiasis Cestodes (tapeworms), as an alternative to praziquantel or niclosamide for adult beef tapeworms and as an alternative to praziquantel for pork...
PML, RAC1, RELA, RET, RPA2, STAT1, Stathmin, Src, and TRIP10. KPNA4. Niclosamide seems to inhibit the STAT3 signalling pathway. Nicotinamide (a type of...
but there has been some success with pyrantel pamoate, levamisole, niclosamide, mebendazole, ivermectin, paracetamol, tiabendazole, and piperazine citrate...
in Illinois, Minnesota, and Michigan, using zequanox, a biopesticide. Niclosamide proves effective in killing invasive zebra mussels in cool waters. The...
Khan AR, Nazir M, Shoukat A (January 2008). "Successful treatment of niclosamide- and praziquantel-resistant beef tapeworm infection with nitazoxanide"...
"Early treatment with fluvoxamine, bromhexine, cyproheptadine, and niclosamide to prevent clinical deterioration in patients with symptomatic COVID-19:...
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