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Salicylanilide information


Salicylanilide[1]
Names
Preferred IUPAC name
2-Hydroxy-N-phenylbenzamide
Other names
2-Hydroxybenzanilide
Identifiers
CAS Number
  • 87-17-2 checkY
3D model (JSmol)
  • Interactive image
Beilstein Reference
 1108135
ChEBI
  • CHEBI:239133
ChEMBL
  • ChEMBL82970
ChemSpider
  • 6610 checkY
ECHA InfoCard 100.001.571 Edit this at Wikidata
EC Number
  • 201-727-8
KEGG
  • C18915
PubChem CID
  • 6872
UNII
  • LHP8NEY345 checkY
CompTox Dashboard (EPA)
  • DTXSID7021784 Edit this at Wikidata
InChI
  • InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) ☒N
    Key: WKEDVNSFRWHDNR-UHFFFAOYSA-N ☒N
  • InChI=1/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16)
    Key: WKEDVNSFRWHDNR-UHFFFAOYAI
SMILES
  • C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O
Properties
Chemical formula
 C13H11NO2
Molar mass 213.236 g·mol−1
Appearance White to off-white crystalline solid
Melting point 136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
GHS labelling:[2]
Pictograms
 GHS07: Exclamation markGHS09: Environmental hazard
Signal word
 Warning
Hazard statements
 H315, H319, H335, H400
Precautionary statements
 P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide.[3]

Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as flukicides. Brominated derivatives including dibromsalan, metabromsalan, and tribromsalan are used as disinfectants with antibacterial and antifungal activities.

  • Bromochlorosalicylanilide
    Bromochlorosalicylanilide
  • Niclosamide
    Niclosamide
  • Oxyclozanide
    Oxyclozanide
  • Rafoxanide
    Rafoxanide
  1. ^ Salicylanilide at chemicalland21.com
  2. ^ "Salicylanilide". pubchem.ncbi.nlm.nih.gov. Retrieved 13 December 2021.
  3. ^ Salicylanilides at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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Salicylanilide

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Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide. Derivatives...

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Oxyclozanide

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Oxyclozanide is a salicylanilide anthelmintic. It is used in the treatment and control of fascioliasis in ruminants mainly domestic animals such as cattle...

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Photodermatitis

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sunscreens) Oxybenzone (UVA and UVB chemical blocker also in sunscreens) Salicylanilide (found in industrial cleaners) St John's wort Hexachlorophene (found...

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Salicylamide

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ethenzamide, labetalol, medroxalol, lopirin, otilonium, oxyclozanide, salicylanilide, niclosamide, and raclopride. 4-Aminosalicylic acid Mesalazine Salsalate...

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Fenbendazole

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hydra treatments, as well as seals. Drug interactions may occur if salicylanilides such as dibromsalan and niclosamide are co-administered. Abortions...

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Anthelmintic

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against Wuchereria bancrofti, Brugia malayi, Brugia timori, and Loa loa Salicylanilide – mitochondrial un-couplers such as Niclosamide and Oxyclozanide, and...

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Niclosamide

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Jayamani E, Kwon B, et al. (April 2015). Planet PJ (ed.). "Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus"....

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Moxidectin

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tubulin benzimidazole Albendazole# Other/unknown quinoline Praziquantel# salicylanilide Niclosamide# aminoacridine Quinacrine butyrophenone Desaspidin chlorophenol...

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Rafoxanide

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Rafoxanide is a salicylanilide used as an anthelmintic. It is most commonly used in ruminant animals to treat adult liver flukes of the species Fasciola...

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List of fungicides

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quintozene rabenzazole [Wikidata] ravuconazole saijunmao saisentong salicylanilide sanguinarine santonin seboctylamine sedaxane silthiofam [Wikidata] silver...

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C13H11NO2

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g/mol, exact mass: 213.0790 u) may refer to: Fenamic acid, or fenamate Salicylanilide This set index page lists chemical structure articles associated with...

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Fasciolosis

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bithionol (Bitin), hexachlorophene (Bilevon), nitroxynil (Trodax) Salicylanilides: closantel (Flukiver, Supaverm), rafoxanide (Flukanide, Ranizole) Benzimidazoles:...

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ATCvet code QP52

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ATCvet code QP52 Anthelmintics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System for veterinary medicinal products...

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Xipamide

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Xipamide is a sulfonamide diuretic drug marketed by Eli Lilly under the trade names Aquaphor (in Germany) and Aquaphoril (in Austria). It is used for the...

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Fabric treatment

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cellulose, starch and polyvinyl acetate. Germicides consist of halogenated salicylanilides, hexachlorophene, neomycin sulfate and benzalkonium quaternary compounds...

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Bromochlorosalicylanilide

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Bromochlorosalicylanilide is an antifungal. It may cause allergic contact dermatitis in some individuals. Weuffen W, Wagner G, Singer D, Petermann M (1966)...

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