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Medical condition
Neuromuscular junction disease
Specialty
Neurology
Neuromuscular junction disease is a medical condition where the normal conduction through the neuromuscular junction fails to function correctly.[1]
^Levitan, Irwin; Kaczmarek, Leonard (August 19, 2015). "Intercellular communication". The Neuron: Cell and Molecular Biology (4th ed.). New York, NY: Oxford University Press. pp. 153–328. ISBN 978-0199773893.
and 25 Related for: Neuromuscular junction disease information
Neuromuscularjunctiondisease is a medical condition where the normal conduction through the neuromuscularjunction fails to function correctly. In diseases...
A neuromuscularjunction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. It allows the motor neuron to transmit...
A neuromusculardisease is any disease affecting the peripheral nervous system (PNS), the neuromuscularjunctions, or skeletal muscles, all of which are...
Myasthenia gravis (MG) is a long-term neuromuscularjunctiondisease that leads to varying degrees of skeletal muscle weakness. The most commonly affected...
acquired neuromusculardiseases including but not limited to immune suppression and drugs that increase the neurotransmitters at the neuromuscularjunction. ...
Below is a partial list of neuromuscular disorders. Duchenne muscular dystrophy Becker muscular dystrophy DMD-associated dilated cardiomyopathy Limb girdle...
stimulations, a physician can assess for the presence of a neuromuscularjunctiondisease, and differentiate between presynaptic and postsynaptic conditions...
evaluate and exclude other diagnostic possibilities. Disorders of the neuromuscularjunction, such as myasthenia gravis (MG) and Lambert–Eaton myasthenic syndrome...
the neuromuscularjunction. Acetylcholinesterase inhibitors are primarily used to treat symptoms of dementia, Alzheimer's disease, Parkinson's disease, and...
variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscularjunction disorders, such as myasthenia...
the neuromuscularjunction. It is activated by a nerve-derived proteoglycan called agrin, which is similarly also required for neuromuscularjunction formation...
acetylcholine from axon endings at the neuromuscularjunction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used...
Thyrotoxic myopathy (TM) is a neuromuscular disorder that develops due to the overproduction of the thyroid hormone thyroxine. Also known as hyperthyroid...
cholinergic. Acetylcholine is the neurotransmitter used at the neuromuscularjunction—in other words, it is the chemical that motor neurons of the nervous...
proteoglycan whose best-characterised role is in the development of the neuromuscularjunction during embryogenesis. Agrin is named based on its involvement in...
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. It is usually...
congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder. The hallmark of the disease is the...
competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscularjunction. It is sold under the trade names Tensilon and Enlon (according...
Muscular dystrophy Certain medications Other neuromuscular disorders The first finding is that junctional rhythms are regular rhythms. This means that...
(MG) is a disease of the neuromuscularjunction resulting in hallmark variability in muscle weakness and fatigability. MG is an autoimmune disease where anomalous...
autoimmune-mediated, which is usually caused by antibodies against the neuromuscularjunction. The exact cause is unknown. However, autoreactive antibodies can...
insufficiency. Diseases disrupting the neuromuscularjunction can cause abnormal muscle fatigue, such as myasthenia gravis, an auto-immune disease. Similar...
myopathy or nemaline rod myopathy) is a congenital, often hereditary neuromuscular disorder with many symptoms that can occur such as muscle weakness,...
excitatory), GABAergic (often inhibitory), cholinergic (e.g. vertebrate neuromuscularjunction), and adrenergic (releasing norepinephrine). Because of the complexity...
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