Depends on the disorder; many currently have no cure[2]
A neuromuscular disease is any disease affecting the peripheral nervous system (PNS),[a] the neuromuscular junctions, or skeletal muscles, all of which are components of the motor unit.[4] Damage to any of these structures can cause muscle atrophy and weakness. Issues with sensation can also occur.
Neuromuscular diseases can be acquired or genetic. Mutations of more than 650 genes have shown to be causes of neuromuscular diseases.[5][6][7] Other causes include nerve or muscle degeneration, autoimmunity, toxins, medications, malnutrition, metabolic derangements, hormone imbalances, infection, nerve compression/entrapment, comprised blood supply, and trauma.[8]
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^ abCite error: The named reference nih was invoked but never defined (see the help page).
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^Katirji, Bashar (2014). "Clinical Assessment in Neuromuscular Disorders". In Katirji, Bashar; Kaminski, Henry J.; Ruff, Robert L. (eds.). Neuromuscular disorders in clinical practice (Second ed.). New York. ISBN 978-1-4614-6567-6.{{cite book}}: CS1 maint: location missing publisher (link)
^Cohen, Enzo; Bonne, Gisèle; Rivier, François; Hamroun, Dalil (December 2021). "The 2022 version of the gene table of neuromuscular disorders (nuclear genome)". Neuromuscular Disorders. 31 (12): 1313–1357. doi:10.1016/j.nmd.2021.11.004.
^Katirji, Bashar; Kaminski, Henry J.; Ruff, Robert L., eds. (2014). Neuromuscular disorders in clinical practice (Second ed.). New York. ISBN 978-1-4614-6567-6.{{cite book}}: CS1 maint: location missing publisher (link)
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and 27 Related for: Neuromuscular disease information
A neuromusculardisease is any disease affecting the peripheral nervous system (PNS), the neuromuscular junctions, or skeletal muscles, all of which are...
Neuromuscular junction disease is a medical condition where the normal conduction through the neuromuscular junction fails to function correctly. In diseases...
A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. It allows the motor neuron to transmit...
on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on NeuromuscularDiseases and the El Escorial...
Below is a partial list of neuromuscular disorders. Duchenne muscular dystrophy Becker muscular dystrophy DMD-associated dilated cardiomyopathy Limb girdle...
Myasthenia gravis (MG) is a long-term neuromuscular junction disease that leads to varying degrees of skeletal muscle weakness. The most commonly affected...
congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder. The hallmark of the disease is the...
Muscular disease can be classified as neuromuscular or musculoskeletal in nature. Some conditions, such as myositis, can be considered both neuromuscular and...
tool in the classification of inherited neuromusculardisease and diagnosis of many other neurogenetic diseases. The role of genetic influences on the...
Neuromuscular medicine is a subspecialty of neurology and physiatry that focuses the diagnosis and management of neuromusculardiseases. The field encompasses...
"Construction of a Quality of Life Questionnaire for slowly progressive neuromusculardisease". Qual Life Res. 24 (11): 2615–23. doi:10.1007/s11136-015-1013-8...
also a factor in some neurodegenerative diseases such as amyotrophic lateral sclerosis or the neuromusculardisease myotonic dystrophy. The sources of genome...
Neuromuscular Disorders is a peer-reviewed medical journal that focuses on neuromusculardisease, including muscular dystrophy, spinal muscular atrophy...
applications. Needle EMG is used as a diagnostics tool for identifying neuromusculardiseases, or as a research tool for studying kinesiology, and disorders of...
Supportive care is focused on preventing disease complications and maintaining independence. Neuromuscular symptoms include muscle weakness and wasting...
Pharmaceuticals has started to investigate it for the treatment of neuromusculardiseases. In 2010, early clinical trials for the treatment of Friedreich's...
volume due to reduced respiratory muscle activity, e.g. in acute neuromusculardisease); this form can also cause type 2 respiratory failure if severe...
function. A subclass of these diseases that have neuromuscular symptoms are known as mitochondrial myopathies. Mitochondrial disease can manifest in many different...
supporting people living with muscular dystrophy, ALS, and related neuromusculardiseases. Founded in 1950 by Paul Cohen, who lived with muscular dystrophy...
underlying lung disease. Furthermore, the vital capacity is used to determine the severity of respiratory muscle involvement in neuromusculardisease, and can...
insufficiency. Diseases disrupting the neuromuscular junction can cause abnormal muscle fatigue, such as myasthenia gravis, an autoimmune disease. Similar,...
Monoglyceride, or monoacylglycerol Myasthenia gravis, a neuromusculardisease Mycoplasma gallisepticum, a disease affecting chickens and other birds Mycoplasma...
monitor disease and prevent secondary injury in states that are insensitive to neurological exam or conditions confounded by sedation, neuromuscular blockade...
to diagnosis and guide treatment for people with neuromuscular diseases. Neuromuscular ultrasound is often combined with electrodiagnosis, and particularly...
Evidence Current Biomarker Findings† Degenerative Neurological and NeuromuscularDisease Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Drug...
(2005). "Electrophysiologic and laboratory aids in the diagnosis of neuromusculardisease". In Ropper AH, Brown RH (eds.). Adams and Victor's Principles of...
(MD) are a genetically and clinically heterogeneous group of rare neuromusculardiseases that cause progressive weakness and breakdown of skeletal muscles...
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