Neonatal herpes simplex, or simply neonatal herpes, is a herpes infection in a newborn baby caused by the herpes simplex virus (HSV), mostly as a result of vertical transmission of the HSV from an affected mother to her baby.[1] Types include skin, eye, and mouth herpes (SEM), disseminated herpes (DIS), and central nervous system herpes (CNS).[2] Depending on the type, symptoms vary from a fever to small blisters, irritability, low body temperature, lethargy, breathing difficulty, and a large abdomen due to ascites or large liver.[2] There may be red streaming eyes or no symptoms.[2]
The cause is HSV 1 and 2.[1] It can infect the unborn baby, but more often passes to the baby during childbirth.[3] Onset is typically in the first six weeks after birth.[2] The baby is at greater risk of being affected if the mother contracts HSV in later pregnancy.[1] In such scenarios a prolonged rupture of membranes or childbirth trauma may increase the risk further.[1]
Globally, it is estimated to affect one in 10,000 births.[4] Around 1 in every 3,500 babies in the United States contract the infection.[5]
^ abcdHussein, Abir; Moss, Nicholas J.; Wald, Anne (2022). "55. Herpes simplex virus genital infection". In Jong, Elaine C.; Stevens, Dennis L. (eds.). Netter's Infectious Diseases (2nd ed.). Philadelphia: Elsevier. pp. 300–307. ISBN 978-0-323-71159-3.
Neonatalherpes simplex, or simply neonatalherpes, is a herpes infection in a newborn baby caused by the herpes simplex virus (HSV), mostly as a result...
the fingers or thumb, herpes simplex keratitis involves the eye, herpesviral encephalitis involves the brain, and neonatalherpes involves any part of...
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members...
horizontal transmission to a sexual partner or the vertical transmission of neonatalherpes to a newborn at term. Since most asymptomatic individuals are unaware...
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known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster)...
childhood AIS. The most common late complication of chickenpox is shingles (herpes zoster), caused by reactivation of the varicella zoster virus decades after...
(also known as a fever blister, oral herpes, and herpes labialis) is a type of herpes infection caused by the herpes simplex virus that affects primarily...
Herpes simplex encephalitis (HSE), or simply herpes encephalitis, is encephalitis due to herpes simplex virus. It is estimated to affect at least 1 in...
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was suggested as a cause in 11 cases of neonatalherpes. Researchers noted that prior to 1997, neonatalherpes reports in Israel were rare, and that the...
herpesvirus 1, Cercopithecine herpesvirus 1, CHV-1), Herpesvirus simiae, or Herpes virus B is the Simplexvirus infecting macaque monkeys. B virus is very similar...
the clinical diagnosis is uncertain and in all cases of suspected neonatalherpes infection: Corneal smears or impression cytology specimens can be analyzed...
Neonatal infections are infections of the neonate (newborn) acquired during prenatal development or within the first four weeks of life. Neonatal infections...
can cause neonatal meningitis, however, HSV-2 accounts for 70% of the cases.[citation needed] Herpes simplex virus is transmitted to neonates mainly during...
typically due to neonatal bacterial infection, although it can also be non-infectious (e.g. chemical exposure). Infectious neonatal conjunctivitis is...
HBLV to HHV-6, in accord with the published provisional classification of herpes viruses. Years later, HHV-6 was divided into subtypes. Early research (1992)...
sixth disease, is an infectious disease caused by certain types of human herpes viruses. Most infections occur before the age of three. Symptoms vary from...
and auditory defects. It may also cause prematurity, low birth weight, neonatal thrombocytopenia, anemia, and hepatitis. The risk of major defects in organogenesis...
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