A multilocus genotype is the combination of alleles found at two or more loci in a single individual.
For example, in a diploid species, if there are two SNP loci and the first locus has alleles A and G, while the second locus has alleles T and C, the multilocus genotype can be represented as {A/G,T/C}. If the genome is not haploid then the multilocus genotype does not necessarily determine which alleles co-occur on chromosomes. In the example, if the two loci are located on the same chromosome the possibilities are either {A-T,G-C} or {A-C,G-T}. Where A-T represents a haplotype with alleles A and T together on one chromosome and G and C together on the other. If the haplotypes are determined the multilocus genotype is referred to as a phased genotype, otherwise it is referred to as unphased. Some authors[1][2] suggest that the term multilocus genotype should only be applied to phased multilocus data while others[3] apply it to unphased multilocus data as well. The combination of alleles at two or more loci on a single chromosome make up a haplotype and the two haplotypes in a diploid individual make up the diplotype (a synonym for a phased multilocus genotype).
^Thompson, Elizabeth A. (2000). "Statistical Inference from Genetic Data on Pedigrees". NSF-CBMS Regional Conference Series in Probability and Statistics. 6. doi:10.1214/cbms/1462106037. ISBN 0-94-0600-49-8. JSTOR 4153187.
^Lange, Kenneth (2003). Mathematical and Statistical Methods for Genetic Analysis. New York: Springer-Verlag. p. 4. ISBN 0-387-95389-2.
^Pritchard, Jonathan K.; Stephens, Matthew; Donnelly, Peter (2000). "Inference of population structure using multilocus genotype data". Genetics. 155 (2): 945–959. doi:10.1093/genetics/155.2.945. PMC 1461096. PMID 10835412.
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the multilocusgenotype is referred to as a phased genotype, otherwise it is referred to as unphased. Some authors suggest that the term multilocus genotype...
Donnelly, P. (June 2000). "Inference of population structure using multilocusgenotype data". Genetics. 155 (2): pp. 945–959. doi:10.1093/genetics/155.2...
individuals and populations. The general principle behind them is to use multilocusgenotypes to assign reference populations as origins of the individuals. This...
a new species, Naja peroescobari, and a recent study (based on a Multilocusgenotype dataset and morphological analyses) suggests that N. melanoleuca...
tissue. It appears that most individual colonies harbor a single multilocusgenotype (i.e. clone). Extensive sampling within colonies confirms that many...
Donnelly, P. (June 2000). "Inference of population structure using multilocusgenotype data". Genetics. 155 (2): 945–959. doi:10.1093/genetics/155.2.945...
Donnelly, Peter (2000-06-01). "Inference of Population Structure Using MultilocusGenotype Data". Genetics. 155 (2): 945–959. doi:10.1093/genetics/155.2.945...
structure, reproduction system Medium to high (N) codominant loci = (Multilocus) genotype Microsatellites, allozymes Fingerprinting. parentage analysis Very...
North American Mallards (A. platyrhynchos) and their hybrids using multilocusgenotypes". Conserv Genet. 10 (6): 1747–1758. Bibcode:2009ConG...10.1747F....
been used to explore the genetic structure of single spores using multilocusgenotyping, AM fungal diversity and adaptation across multiple grassland communities...
degrees of recent African immigration. This suggests that the Duffy negative genotype evolved in Sub-Saharan Africa and was subsequently positively selected...
Christian; Leray, Philippe (2011-12-13). "Visualization of Pairwise and Multilocus Linkage Disequilibrium Structure Using Latent Forests". PLoS ONE. 6 (12):...
Leptospira lead to the development of multilocus VNTR (Variable Number of Tandem Repeats) typing and multilocus sequence typing (MLST) for species level...
G, Estoup A, Solignac M (December 1999). "New methods employing multilocusgenotypes to select or exclude populations as origins of individuals". Genetics...
Donnelly P (June 2000). "Inference of population structure using multilocusgenotype data". Genetics. 155 (2): 945–59. doi:10.1093/genetics/155.2.945...
"A single domestication for potato based on multilocus amplified fragment length polymorphism genotyping". PNAS. 102 (41): 14694–99. Bibcode:2005PNAS...
"A single domestication for potato based on multilocus amplified fragment length polymorphism genotyping". PNAS. 102 (41): 14694–99. Bibcode:2005PNAS...
aenibacillus larvae , the causative agent of American foulbrood, using a new multilocus sequence typing scheme". Environmental Microbiology. 17 (4): 1414–1424...
and locally common parasite in New Zealand lakes and streams. Multilocus allozyme genotype data show that this Microphallus is a single outbred species...
association aim to test whether single-locus alleles or genotype frequencies or more generally, multilocus haplotype frequencies differ between two groups of...
Ascomycota. de Hoog GS, Dukik K, Monod M, et al. (2017). "Toward a novel multilocus phylogenetic taxonomy for the dermatophytes". Mycopathologia. 182 (1–2):...
unique 14-locus allozyme genotype specific to the colder regions of Spain. Neither the "xeric" nor monomorphic "mesic" genotypes described in California...
mechanism would be negative or purifying selection against poorly fit multilocusgenotypes. Therefore, the hybrizymes that increase in frequency could be modifier...
analysis of dairy and nondairy Lactococcus lactis isolates, using a novel multilocus sequence analysis scheme and (GTG)5-PCR fingerprinting". Applied and Environmental...
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