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List of investigational antidepressants information



This is a list of investigational antidepressants, or antidepressants that are currently under development for clinical use in the treatment of mood disorders but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses. All drugs listed are specifically under development for major depressive disorder (MDD) and/or treatment-resistant depression (TRD) unless noted otherwise. Other forms of depression may include bipolar depression and postpartum depression.

Drugs that have been investigated but are not currently in development as antidepressants are given in italic.

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List of investigational antidepressants

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This is a list of investigational antidepressants, or antidepressants that are currently under development for clinical use in the treatment of mood disorders...

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Lists of drugs

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antidepressants List of investigational analgesics List of investigational antidepressants List of investigational antipsychotics List of investigational anxiolytics...

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Lists of investigational drugs

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of investigational drugs: List of investigational analgesics List of investigational antidepressants List of investigational antipsychotics List of investigational...

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Atypical antidepressant

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antidepressants. Second-generation antidepressant Pharmacology of antidepressants List of antidepressants Feighner JP (1999). "Mechanism of action of...

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List of investigational antipsychotics

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This is a list of investigational antipsychotics, or antipsychotics that are currently under development for clinical use but are not yet approved. Chemical/generic...

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Antidepressant

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antidepressant Depression and natural therapies List of investigational antidepressants Jennings L (2018). "Antidepressants". In Grossberg GT, Kinsella LJ (eds.)...

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List of investigational analgesics

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This is a list of investigational analgesics, or analgesics that are currently under development for clinical use but are not yet approved. Chemical/generic...

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NMDA receptor antagonist

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regression is 573 μM). Xenon: an anesthetic. List of investigational antidepressants Discovery and development of memantine and related compounds Pender JW...

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Navacaprant

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trials for this indication. κ-Opioid receptor § Antagonists List of investigational antidepressants "BlackThorn Therapeutics Advances Phase 2 Clinical Development...

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List of investigational sleep drugs

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This is a list of investigational sleep drugs, or drugs for the treatment of sleep disorders that are currently under development for clinical use but...

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GABAA receptor negative allosteric modulator

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modulator AMPA receptor positive allosteric modulator List of investigational antidepressants Johnston GA (2005). "GABA(A) receptor channel pharmacology"...

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AMPA receptor positive allosteric modulator

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positive allosteric modulator NMDA receptor antagonist List of investigational antidepressants Lee K, Goodman L, Fourie C, Schenk S, Leitch B, Montgomery...

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List of investigational anxiolytics

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This is a list of investigational anxiolytics, or anxiolytics that are currently under development for clinical use but are not yet approved. Chemical/generic...

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Ampakine

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to treat sleep deprivation-induced cognitive decline. List of investigational antidepressants Froestl W, Muhs A, Pfeifer A (2012). "Cognitive enhancers...

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Zelquistinel

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2019, the drug had completed a phase IIa clinical trial. List of investigational antidepressants Apimostinel "NMDA receptor modulators - AdisInsight". adisinsight...

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List of investigational attention deficit hyperactivity disorder drugs

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This is a list of investigational attention deficit hyperactivity disorder drugs, or drugs that are currently under development for clinical use in the...

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Arketamine

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Hengrui Medicine in China. List of investigational antidepressants Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC...

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Itruvone

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as a nasal spray for the treatment of major depressive disorder. List of investigational antidepressants List of neurosteroids § Pheromones and pherines...

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Apimostinel

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such as ketamine. List of investigational antidepressants Zelquistinel "Naurex's Novel Antidepressant GLYX-13 Recognized as One of Windhover's Top 10...

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Seltorexant

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investigational short-acting orexin receptor antagonist List of investigational antidepressants § Orexin receptor antagonists List of investigational...

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Rapastinel

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the death of CA1, CA3, and dentate gyrus pyramidal neurons under glucose and oxygen-deprived conditions. List of investigational antidepressants Henter ID...

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JDTic

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risky inhibitors of the KOR than are non-inactivating antagonists. κ-Opioid receptor § Antagonists List of investigational antidepressants Thomas JB, Atkinson...

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Posovolone

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descriptor of "antidepressant". Posovolone was originally developed by Purdue Pharma. List of investigational antidepressants List of investigational sleep...

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Rislenemdaz

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November 2016 that the drug failed to demonstrate efficacy. List of investigational antidepressants Ibrahim L, Diaz Granados N, Jolkovsky L, Brutsche N, Luckenbaugh...

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