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Molecular probe information


A compass of molecular probes

A molecular probe is a group of atoms or molecules used in molecular biology or chemistry to study the properties of other molecules or structures. If some measurable property of the molecular probe used changes when it interacts with the analyte (such as a change in absorbance), the interactions between the probe and the analyte can be studied. This makes it possible to indirectly study the properties of compounds and structures which may be hard to study directly.

The choice of molecular probe will depend on which compound or structure is being studied as well as on what property is of interest. Radioactive DNA or RNA sequences are used in molecular genetics to detect the presence of a complementary sequence by molecular hybridization.[1]

  1. ^ "Cancerweb Molecular Probe Definition".

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Molecular probe

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A molecular probe is a group of atoms or molecules used in molecular biology or chemistry to study the properties of other molecules or structures. If...

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Molecular Probes

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Molecular Probes was a biotechnology company located in Eugene, Oregon specializing in fluorescence. The company was founded in 1975 by Richard and Rosaria...

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Probe

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spacecraft Molecular probe, a group of atoms or molecules used to study other molecules Hybridization probe, a labeled fragment of DNA or RNA, Test probe (electronics)...

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Hybridization probe

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In molecular biology, a hybridization probe (HP) is a fragment of DNA or RNA, usually 15–10000 nucleotides long, which can be radioactively or fluorescently...

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Digitalis

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species, and is extracted from D. lanata. Digoxigenin can be used as a molecular probe to detect mRNA in situ and label DNA, RNA, and oligonucleotides. It...

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Molecular Inversion Probe

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Molecular Inversion Probe (MIP) belongs to the class of Capture by Circularization molecular techniques for performing genomic partitioning, a process...

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PEG 400

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D. Hollander; P. Krugliak; K. Katz (1990). "PEG 400, a hydrophilic molecular probe for measuring intestinal permeability". Gastroenterology. 98 (1): 39–46...

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Dick Haugland

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He is the original author of the authoritative volume on molecular probes, The Molecular Probes Handbook, now in its 11th edition. Dick Haugland was born...

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Molecular biology

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Molecular biology /məˈlɛkjʊlər/ is a branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including...

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Chemical probe

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phenotype of the cell, a molecular probe can be used to determine the function of the protein with which it interacts. Chemical Probes Portal Arrowsmith CH...

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Cycling probe technology

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Cycling probe technology (CPT) is a molecular biological technique for detecting specific DNA sequences. CPT operates under isothermal conditions. In...

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Molecular beacon

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Molecular beacons, or molecular beacon probes, are oligonucleotide hybridization probes that can report the presence of specific nucleic acids in homogenous...

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Molecular and Cellular Probes

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Molecular and Cellular Probes is a peer-reviewed scientific journal covering research on the location, diagnosis, and monitoring of inherited and infectious...

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Molecule

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different biochemical activities. Molecular spectroscopy deals with the response (spectrum) of molecules interacting with probing signals of known energy (or...

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Scanning probe microscopy

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Scanning probe microscopy (SPM) is a branch of microscopy that forms images of surfaces using a physical probe that scans the specimen. SPM was founded...

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Fluorophore

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; Liu, C.; He, W. (2013), "Fluorophores and Their Applications as Molecular Probes in Living Cells", Curr. Org. Chem., 17 (6): 564–579, doi:10.2174/1385272811317060003...

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Oligonucleotide

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synthesis, polymerase chain reaction (PCR), DNA sequencing, molecular cloning and as molecular probes. In nature, oligonucleotides are usually found as small...

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SYBR Green I

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cyanine dye used as a nucleic acid stain in molecular biology. The SYBR family of dyes is produced by Molecular Probes Inc., now owned by Thermo Fisher Scientific...

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Alexa Fluor

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Alexa Fluor family of fluorescent dyes is a series of dyes invented by Molecular Probes, now a part of Thermo Fisher Scientific, and sold under the Invitrogen...

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Nucleic acid test

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thereafter. In 2013, Seelig's group published a paper about fluorescent molecular probes which also utilizes the toehold exchange reaction. This enabled the...

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RiboGreen

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acids, including both RNA and DNA. It is synthesized and marketed by Molecular Probes/Invitrogen (a division of Life Technologies, now part of Thermo Fisher...

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Ans

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8-Anilinonaphthalene-1-sulfonic acid, a fluorescent chemical compound used as a molecular probe Anthocyanidin synthase, an enzyme in the leucocyanidin biosynthesis...

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Hoechst stain

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1177/24.1.943439. PMID 943439. "Hoechst Stains" (PDF). Invitrogren (Molecular Probes). Archived from the original (PDF) on 2009-04-19. Portugal, J; Waring...

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Spin probe

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A spin probe is a molecule with stable free radical character that carries a functional group. This group can be used to couple the probe to another molecule...

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Nanotechnology

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to as molecular nanotechnology. Nanotechnology defined by scale includes fields of science such as surface science, organic chemistry, molecular biology...

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Southern blot

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high-molecular-weight DNA strands into smaller fragments. This is done by adding the desired amount of  DNA which can be changed according to the probe used...

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