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Methyl methanesulfonate information


Methyl methanesulfonate
Skeletal formula
Skeletal formula
Ball-and-stick model
Ball-and-stick model
Names
Preferred IUPAC name
Methyl methanesulfonate
Other names
Methanesulfonic acid methyl ester
Methyl mesylate
MMS
Identifiers
CAS Number
  • 66-27-3 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:25255 ☒N
ChemSpider
  • 4013 ☒N
ECHA InfoCard 100.000.568 Edit this at Wikidata
EC Number
  • 200-625-0
KEGG
  • C19181 checkY
MeSH D008741
PubChem CID
  • 4156
UNII
  • AT5C31J09G checkY
CompTox Dashboard (EPA)
  • DTXSID7020845 Edit this at Wikidata
InChI
  • InChI=1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3 ☒N
    Key: MBABOKRGFJTBAE-UHFFFAOYSA-N ☒N
  • InChI=1/C2H6O3S/c1-5-6(2,3)4/h1-2H3
    Key: MBABOKRGFJTBAE-UHFFFAOYAK
SMILES
  • COS(=O)(=O)C
Properties
Chemical formula
C2H6O3S
Molar mass 110.13 g/mol
Density 1.3 g/mL at 25 °C
Boiling point 202 to 203 °C (396 to 397 °F; 475 to 476 K)
Related compounds
Related compounds
Ethyl methanesulfonate, dimethyl sulfone, dimethyl sulfate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Methyl methanesulfonate (MMS), also known as methyl mesylate, is an alkylating agent and a carcinogen. It is also a suspected reproductive toxicant, and may also be a skin/sense organ toxicant.[1] It is used in cancer treatment.[2]

  1. ^ Scorecard Pollution Information Site: Methyl Methanesulfonate Scorecard.org Accessed 14 Feb 08
  2. ^ Medical.Webends.com: Methyl Methanesulfonate Archived 2008-02-15 at the Wayback Machine Medical.webends.com Accessed 14 Feb 08

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Methyl methanesulfonate

Last Update:

Methyl methanesulfonate (MMS), also known as methyl mesylate, is an alkylating agent and a carcinogen. It is also a suspected reproductive toxicant, and...

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MMS

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Magnetospheric Multiscale Mission, NASA Massachusetts Medical Society Methyl methanesulfonate Moment magnitude scale of earthquake energy Multiscale Modeling...

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Dimethyl sulfoxide

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DMS), the corresponding sulfate: a mutagenic alkylating compound Methyl methanesulfonate, another methylating agent Gloria Ramirez, also known as the "Toxic...

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Herpes simplex virus

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occurs upon exposure to different DNA damaging agents, including methyl methanesulfonate, trimethylpsoralen (which causes inter-strand DNA cross-links)...

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Saccharomyces cerevisiae

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Rad52 mutants have increased sensitivity to killing by X-rays, Methyl methanesulfonate and the DNA cross-linking agent 8-methoxypsoralen-plus-UVA, and...

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Mesylate

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spot in Antarctica were found to have tiny inclusions of magnesium methanesulfonate dodecahydrate. This natural phase is recognized as the mineral ernstburkeite...

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IARC group 2A

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5-Methoxypsoralen Methyleugenol Methyl methanesulfonate Mercaptobenzothiozole MNNG (N-Methyl-N'-nitro-N-nitrosoguanidine) N-Methyl-N-nitrosourea Nitrate or nitrite...

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BRCA2

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repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment". Proc. Natl. Acad. Sci. U.S.A. 95 (9): 5287–92. Bibcode:1998PNAS...

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Tetrahymena thermophila

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Rad51 gene expression. Treatment with the DNA alkylating agent methyl methanesulfonate also resulted in substantially elevated Rad 51 protein levels....

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C2H6O3S

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may refer to: Dimethyl sulfite Ethanesulfonic acid (esylic acid) Methyl methanesulfonate This set index page lists chemical structure articles associated...

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Insect reproductive system

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have increase sensitivity to the DNA damaging agents x-rays, UV, methyl methanesulfonate and nitrogen mustard. These results link meiotic recombination...

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Mitotic recombination

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mutant yeast cells have increased sensitivity to killing by X-rays, methyl methanesulfonate and the DNA crosslinking agent 8-methoxypsoralen-plus-UV light...

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Tetrahymena

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Rad51 gene expression. Treatment with the DNA alkylating agent methyl methanesulfonate also resulted in substantially elevated Rad 51 protein levels....

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Somatic recombination

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simultaneously hypersensitive to the DNA damaging agents mitomycin C and/or methyl methanesulfonate. The mutants were also deficient in somatic homologous recombination...

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Sulfonate

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drug zonisamide. Tisocromide is an example of a sultone. Mesylate (methanesulfonate), CH3−SO−3 Triflate (trifluoromethanesulfonate), CF3−SO−3 Ethanesulfonate...

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Ethyl methanesulfonate

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Ethyl methanesulfonate (EMS) is an organosulfur compound with the formula CH3SO3C2H5. It is the ethyl ester of methanesulfonic acid. A colorless liquid...

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Methanesulfonyl chloride

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amines. The simplest organic sulfonyl chloride, it is used to make methanesulfonates and to generate the elusive molecule sulfene (methylenedioxosulfur(VI))...

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DNA ligase

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increased sensitivity to both UV irradiation and the alkylating agent methyl methanesulfonate indicating that DNA ligase is employed in the repair of the DNA...

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Bloom syndrome

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BLM cells are sensitive to DNA damaging agents such as UV and methyl methanesulfonate, indicating deficient repair capability. At the level of the chromosomes...

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California Proposition 65 list of chemicals

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Methyl iodide 74-88-4 Methyl isobutyl ketone (MIBK) 108-10-1 Methyl isocyanate (MIC) 624-83-9 Methyl mercury and compounds – Methyl methanesulfonate 66-27-3...

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Adaptive response

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is required for reactivation of MMS-treated (methylating agent methyl methanesulfonate) single-stranded phage and since there are no lesions to be removed...

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IARC group 2B

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acrylate Ethylbenzene Ethylene dichloride 2-Ethylhexyl acrylate Ethyl methanesulfonate Foreign bodies, implanted in tissues Polymeric, prepared as thin smooth...

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Dimethyl sulfite

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observed to any great extent. SOCl2 + 2 CH3OH → (CH3O)2SO + 2 HCl Methyl methanesulfonate, a chemical with the same molecular formula but different arrangement...

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MMS22L

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Methyl methanesulfonate-sensitivity protein 22-like also known as MMS22-like, DNA repair protein is a protein that in humans is encoded by the MMS22L...

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RecQ helicase

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Bloom syndrome are sensitive to DNA damaging agents such as UV and methyl methanesulfonate indicating deficient DNA repair capability. The budding yeast Saccharomyces...

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RAD51

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repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment". Proceedings of the National Academy of Sciences of...

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Gcn2

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entry into S phase upon ultraviolet (UV) radiation and exposure to methyl methanesulfonate (MMS). Thereby the cell prevents passing the G1 checkpoint and...

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Ataxia telangiectasia and Rad3 related

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sensitivity to killing by exposure to the DNA damaging agents UV , and methyl methanesulfonate. Deficiency of mei-41(ATR) also causes reduced spontaneous allelic...

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Botryosphaeran

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Botryosphaeran exhibited antigenotoxic activity against damage induced by methyl methanesulfonate, in normal and tumorigenic (Jurkat) human lymphocytes. The absence...

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