IARC group 2A agents are substances and exposure circumstances that have been classified as probable carcinogens by the International Agency for Research on Cancer (IARC).[1] This designation is applied when there is limited evidence of carcinogenicity in humans, as well as sufficient evidence of carcinogenicity in experimental animals. In some cases, an agent may be classified in this group when there is inadequate evidence of carcinogenicity in humans along with sufficient evidence of carcinogenicity in experimental animals and strong evidence that the carcinogenesis is mediated by a mechanism that also operates in humans. Exceptionally, an agent may be classified in this group solely on the basis of limited evidence of carcinogenicity in humans.
This list is focusing on the hazard linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their risk into account, which is the probability of causing a cancer given the level of exposure to this carcinogenic agent.[2] The list is uptodate as of January 2024.[3]
^"List of Classifications, Agents classified by the IARC Monographs, Volumes 1–124". IARC Monographs on the Evaluation of Risk to Humans. IARC. July 7, 2019. Retrieved July 14, 2019.
^"IARC monographs preamble (as amended in 2019)" (PDF). International Agency for Research on Cancer (IARC). Retrieved August 18, 2023. A cancer hazard is an agent that is capable of causing cancer, whereas a cancer risk is an estimate of the probability that cancer will occur given some level of exposure to a cancer hazard.
^"List of Classifications – IARC Monographs on the Identification of Carcinogenic Hazards to Humans". monographs.iarc.who.int. Retrieved 2024-02-01.
IARCgroup2A agents are substances and exposure circumstances that have been classified as probable carcinogens by the International Agency for Research...
devices Welding fumes and UV radiation IARCgroup2AIARCgroup 2B IARCgroup 3 This evaluation applies to the group of compounds as a whole and not necessarily...
IARCgroup 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International...
IARCgroup 3 substances, chemical mixtures and exposure circumstances are those that can not be classified in regard to their carcinogenicity to humans...
International Agency for Research on Cancer (IARC) classified glyphosate as "probably carcinogenic in humans" (category 2A) based on epidemiological studies, animal...
for Research on Cancer (IARC) of the World Health Organization (WHO) classifies processed meat as carcinogenic to humans (Group 1), based on "sufficient...
Agency for Research on Cancer (IARC), cobalt metal with tungsten carbide is "probably carcinogenic to humans" (IARCGroup2A Agent), whereas cobalt metal...
Chloral hydrate is a geminal diol with the formula Cl3C−CH(OH)2. It was first used as a sedative and hypnotic in Germany in the 1870s. Over time it was...
The chemical composition of the electronic cigarette aerosol varies across and within manufacturers. Limited data exists regarding their chemistry. However...
2015, the International Agency for Research on Cancer classified DDT as Group2A "probably carcinogenic to humans". Previous assessments by the U.S. National...
the respiratory tract. The International Agency for Research on Cancer (IARC) has determined that coal-tar creosote is probably carcinogenic to humans...
Chloral, also known as trichloroacetaldehyde or trichloroethanal, is the organic compound with the formula Cl3CCHO. This aldehyde is a colourless liquid...
Benzoyl chloride, also known as benzenecarbonyl chloride, is an organochlorine compound with the formula C7H5ClO. It is a colourless, fuming liquid with...
2-Mercaptobenzothiazole is an organosulfur compound with the formula C6H4(NH)SC=S. A white solid, it is used in the sulfur vulcanization of rubber. The...
there is in animals. It is classified as a Group2A (probably carcinogenic to humans) carcinogen by the IARC. Experimentation with animals has suggested...
Acrolein (systematic name: propenal) is the simplest unsaturated aldehyde. It is a colorless liquid with a foul and acrid aroma. The smell of burnt fat...
ISBN 978-3-11-046984-4. PMID 29394020. "Cisplatin". Drug Information Portal. U.S. National Library of Medicine. IARC Monograph: "Cisplatin" Portal: Medicine...
inhalation of the vapour, ingestion, or percutaneous absorption. The IARC lists it in Group2A (Probably carcinogenic to humans), and it has specifically been...
with the chemical formula C6H5CH=CH2. Its structure consists of a vinyl group as substituent on benzene. Styrene is a colorless, oily liquid, although...
carcinogen by U.S. government agencies and classified as a Group2A carcinogen by the IARC. The Occupational Safety and Health Administration and the...
Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro-nitrosourea compound...
Dichloromethane Fact Sheet Dichloromethane at National Toxicology Program IARC Summaries & Evaluations Vol. 71 (1999) Canadian Environmental Protection...
Attainment Program List of IARCGroup 1 carcinogens List of IARCGroup2A carcinogens List of IARCGroup 2B carcinogens List of IARCGroup 3 possible carcinogens...
classified as "probably carcinogenic to humans" (Group2A) by the International Agency for Research on Cancer (IARC). There is a possibility that it is carcinogenic...
Epichlorohydrin is classified by several international health research agencies and groups as a probable or likely carcinogen in humans. Prolonged oral consumption...
Indium phosphide (InP) is a binary semiconductor composed of indium and phosphorus. It has a face-centered cubic ("zincblende") crystal structure, identical...
Tetrafluoroethylene (TFE) is a fluorocarbon with the chemical formula C2F4. It is the simplest perfluorinated alkene. This gaseous species is used primarily...
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