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Membranoproliferative glomerulonephritis information


Membranoproliferative glomerulonephritis
Other namesMesangiocapillary glomerulonephritis[1]
Micrograph of glomerulus in membranoproliferative glomerulonephritis with increased mesangial matrix and increased mesangial cellularity. Kidney biopsy. PAS stain.
SpecialtyNephrology

Membranoproliferative glomerulonephritis (MPGN) is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening,[2] activating the complement system and damaging the glomeruli.

MPGN accounts for approximately 4% of primary renal causes of nephrotic syndrome in children and 7% in adults.[3]

It should not be confused with membranous glomerulonephritis, a condition in which the basement membrane is thickened, but the mesangium is not.

  1. ^ Colville D, Guymer R, Sinclair RA, Savige J (August 2003). "Visual impairment caused by retinal abnormalities in mesangiocapillary (membranoproliferative) glomerulonephritis type II ("dense deposit disease")". Am. J. Kidney Dis. 42 (2): E2–5. doi:10.1016/S0272-6386(03)00665-6. PMID 12900843.
  2. ^ "membranoproliferative glomerulonephritis" at Dorland's Medical Dictionary
  3. ^ Habib R, Gubler MC, Loirat C, Mäiz HB, Levy M (1975). "Dense deposit disease: a variant of membranoproliferative glomerulonephritis". Kidney Int. 7 (4): 204–15. doi:10.1038/ki.1975.32. PMID 1095806.

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Membranoproliferative glomerulonephritis

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Glomerulonephritis

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Complement component 3

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types of kidney disease such as post-infectious glomerulonephritis, membranoproliferative glomerulonephritis, and shunt nephritis. Factor H is the primary...

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Nephrotic syndrome

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people, although an auto-immune mechanism is suspected. Membranoproliferative glomerulonephritis (MPGN): is the inflammation of the glomeruli along with...

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Cryoglobulinemia

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lupus erythematosus is associated with low C3 and C4. Membranoproliferative glomerulonephritis usually has low C3. The mechanism of complement deficiency...

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Hypoalbuminemia

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syndromes are commonly diagnosed as minimal change disease, membranoproliferative glomerulonephritis, or focal segmental glomerulosclerosis. In adults, on the...

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Anaerococcus

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Hepatitis C

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Light chain deposition disease

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