structure with developmental contribution from neural crest
heart
atrium
intestine
n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
protein binding
protein homodimerization activity
protein heterodimerization activity
Cellular component
extracellular region
protein-containing complex
Biological process
complement activation, alternative pathway
regulation of complement activation
negative regulation of protein binding
positive regulation of cytolysis
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
81494
n/a
Ensembl
ENSG00000134389
n/a
UniProt
Q9BXR6
n/a
RefSeq (mRNA)
NM_030787
n/a
RefSeq (protein)
NP_110414
n/a
Location (UCSC)
Chr 1: 196.98 – 197.01 Mb
n/a
PubMed search
[2]
n/a
Wikidata
View/Edit Human
Complement factor H-related protein 5 is a protein that in humans is encoded by the CFHR5 gene.[3][4][5]
^ abcGRCh38: Ensembl release 89: ENSG00000134389 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^McRae JL, Cowan PJ, Power DA, Mitchelhill KI, Kemp BE, Morgan BP, Murphy BF (Mar 2001). "Human factor H-related protein 5 (FHR-5). A new complement-associated protein". J Biol Chem. 276 (9): 6747–54. doi:10.1074/jbc.M007495200. PMID 11058592.
^McRae JL, Murphy BE, Eyre HJ, Sutherland GR, Crawford J, Cowan PJ (Jun 2002). "Location and structure of the human FHR-5 gene". Genetica. 114 (2): 157–61. doi:10.1023/A:1015114512924. PMID 12041828. S2CID 19274329.
H-related protein 5 is a protein that in humans is encoded by the CFHR5 gene. CFHR5 is structurally related to complement factor H which plays an important...
protein 5 (CFHR5) nephropathy is a form of inherited kidney disease which is endemic in Cyprus and is caused by a mutation in the gene CFHR5. It is thought...
of host (as opposed to bacterial) cells from complement-mediated damage. CFHR5 (Complement factor H-Related protein 5) is able to bind to act as a cofactor...
Global Information
