G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
circadian rhythm
signal transduction
chemical synaptic transmission
G protein-coupled receptor signaling pathway
negative regulation of cGMP-mediated signaling
positive regulation of circadian rhythm
camera-type eye development
negative regulation of neuron apoptotic process
positive regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of insulin secretion
negative regulation of cytosolic calcium ion concentration
negative regulation of transmission of nerve impulse
positive regulation of transmission of nerve impulse
regulation of neuronal action potential
negative regulation of delayed rectifier potassium channel activity
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4544
244701
Ensembl
ENSG00000134640
ENSMUSG00000050901
UniProt
P49286
Q8CIQ6 Q3SXF8
RefSeq (mRNA)
NM_005959
NM_145712
RefSeq (protein)
NP_005950
NP_663758
Location (UCSC)
Chr 11: 92.97 – 92.99 Mb
Chr 9: 15.74 – 15.79 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Melatonin receptor 1B, also known as MTNR1B, is a protein that in humans is encoded by the MTNR1B gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000134640 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000050901 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: MTNR1B melatonin receptor 1B".
^Reppert SM, Godson C, Mahle CD, Weaver DR, Slaugenhaupt SA, Gusella JF (Sep 1995). "Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor". Proceedings of the National Academy of Sciences of the United States of America. 92 (19): 8734–38. Bibcode:1995PNAS...92.8734R. doi:10.1073/pnas.92.19.8734. PMC 41041. PMID 7568007.
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Global Information
