Maraviroc, sold under the brand names Selzentry (US) and Celsentri (EU), is an antiretroviral medication used to treat HIV infection.[2][3] It is taken by mouth.[2][3] It is in the CCR5 receptor antagonist class.[2][3]
It was approved for medical use in the United States in August 2007,[2] and in the European Union in September 2007.[3]
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
^ abcdefghi"Selzentry- maraviroc tablet, film coated Selzentry- maraviroc solution". DailyMed. 18 July 2018. Retrieved 31 July 2020.
^ abcde"Celsentri EPAR". European Medicines Agency (EMA). 17 September 2018. Retrieved 31 July 2020.
^Abel S, Russell D, Whitlock LA, Ridgway CE, Nedderman AN, Walker DK (April 2008). "Assessment of the absorption, metabolism and absolute bioavailability of maraviroc in healthy male subjects". British Journal of Clinical Pharmacology. 65 (Suppl 1): 60–7. doi:10.1111/j.1365-2125.2008.03137.x. PMC 2311408. PMID 18333867.
^Abel S, Back DJ, Vourvahis M (2009). "Maraviroc: pharmacokinetics and drug interactions". Antiviral Therapy. 14 (5): 607–18. doi:10.1177/135965350901400514. PMID 19704163. S2CID 29064286.
Maraviroc, sold under the brand names Selzentry (US) and Celsentri (EU), is an antiretroviral medication used to treat HIV infection. It is taken by mouth...
and Pfizer with maraviroc.[citation needed] All of the compounds reached clinical trials in humans;[citation needed] only maraviroc has been approved[vague]...
Plough), Aplaviroc (GW-873140) (GlaxoSmithKline) and Maraviroc (UK-427857) (Pfizer). Maraviroc was approved for use by the FDA in August 2007. It is...
Vicriviroc, similar to maraviroc, is currently undergoing clinical trials for FDA approval. Aplaviroc, an agent similar to maraviroc and vicriroc. Clinical...
negative allosteric modulators (NAM) lower agonist affinity and/or efficacy. Maraviroc is a medicine that modulates CCR5. Fenobam, raseglurant and dipraglurant...
course of the infection. Alternatively to gene therapy, medication such as maraviroc (MVC) is being used to bind with CCR5 particles, blocking the entry of...
creating new blood vessels in the body. Another discovery made using HTS is Maraviroc. It is an HIV entry inhibitor, and slows the process and prevents HIV...
Roy, A.; Dasarathy, S.; Kordower, J. H.; Pahan, K. (2019). "Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the...
targets include the calcium-mimicking cinacalcet and the HIV treatment maraviroc. Allosteric proteins are involved in, and are central in many diseases...
can physically block gp120 from binding to a cell. Only one such agent, Maraviroc, which binds the co-receptor CCR5 is currently licensed and in clinical...