CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins since they span the cell membrane seven times. To date, ten true members of the CC chemokine receptor subfamily have been described. These are named CCR1 to CCR10 according to the IUIS/WHO Subcommittee on Chemokine Nomenclature.
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CCchemokinereceptors (or beta chemokinereceptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine...
Chemokinereceptors are divided into different families, CXC chemokinereceptors, CCchemokinereceptors, CX3C chemokinereceptors and XC chemokine receptors...
chemokine family. They represent one subfamily of chemokinereceptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM)...
CC, CX3C and C. All of these proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors...
C-C chemokinereceptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. CCR2 is a CC chemokine...
encodes a member of the beta chemokinereceptor family, which belongs to G protein-coupled receptors. The ligands of this receptor include CCL3 (or MIP-1 alpha)...
CCR4+receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) "ChemokineReceptors: CCR4". IUPHAR Database of Receptors and Ion...
monocyte-chemotactic protein 3 (MCP3). CCL7 is a small protein that belongs to the CCchemokine family and is most closely related to CCL2 (previously called MCP1)....
beta chemokinereceptors family of integral membrane proteins. It is a G protein–coupled receptor which functions as a chemokinereceptor in the CC chemokine...
Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CCchemokine family. This chemokine is also known as 6Ckine (because it has...
clunky acronym was only made to fit the name. CCL5 belongs to the CC subfamily of chemokines, due to its adjacent cysteines near N terminus. It is an 8kDa...
the beta chemokinereceptor family. CCR9 is a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors, such as...
CX3C motif chemokinereceptor 1 (CX3CR1), also known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13), is a transmembrane protein...
acid in CXC chemokines and are adjacent in CCchemokines. CCR10 is a chemokinereceptor. Its ligands are CCL27 and CCL28. This receptor is normally expressed...
C-X-C chemokinereceptor type 4 (CXCR-4) also known as fusin or CD184 (cluster of differentiation 184) is a protein that in humans is encoded by the CXCR4...
through the CC chemokinereceptors (CCR)-2 and -3. J Immunol. 1996;157:5613–5626 Naruse et al., A YAC contig of the human CCchemokine genes clustered...
The eotaxins are a CCchemokine subfamily of eosinophil chemotactic proteins. Eotaxin is a special CCchemokine because it primarily attracts eosinophils...
seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment...
inflammatory properties. CCL4 is a small cytokine that belongs to the CCchemokine subfamily. CCL4 is being secreted under mitogenic signals and antigens...
Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells,...
Chemokine (C-C motif) ligand 18 (CCL18) is a small cytokine belonging to the CCchemokine family. The functions of CCL18 have been well studied in laboratory...
Specifically, chemokines attract lymphocytes to sites of infection or damage. This protein binds to several chemokinereceptors including chemokine binding...
Cytokine receptors are receptors that bind to cytokines. In recent years, the cytokine receptors have come to demand the attention of more investigators...
Poteligeo, is a humanized, afucosylated monoclonal antibody targeting CCchemokinereceptor type 4 (CCR4). It is given by injection into a vein. The most common...