In molecular biology the LysM domain is a protein domain found in a wide variety of extracellular proteins and receptors. The LysM domain is named after the Lysin Motif which was the original name given to the sequence motif identified in bacterial proteins. The region was originally identified as a C-terminal repeat found in the Enterococcus hirae muramidase.[1] The LysM domain is found in a wide range of microbial extracellular proteins, where the LysM domain is thought to provide an anchoring to extracellular polysaccharides such as peptidoglycan and chitin. LysM domains are also found in plant receptors, including NFP, the receptor for Nod factor which is necessary for the root nodule symbiosis between legumes and symbiotic bacteria.[2] The LysM domain is typically between 44 and 65 amino acid residues in length.[3] The structure of the LysM domain showed that it is composed of a pair of antiparallel beta strands separated by a pair of short alpha helices.[4]
^Joris B, Englebert S, Chu CP, Kariyama R, Daneo-Moore L, Shockman GD, Ghuysen JM (March 1992). "Modular design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin". FEMS Microbiology Letters. 70 (3): 257–64. doi:10.1016/0378-1097(92)90707-u. PMID 1352512.
^Arrighi, Jean-François; Barre, Annick; Ben Amor, Besma; Bersoult, Anne; Soriano, Lidia Campos; Mirabella, Rossana; de Carvalho-Niebel, Fernanda; Journet, Etienne-Pascal; Ghérardi, Michèle; Huguet, Thierry; Geurts, René (2006). "The Medicago truncatula Lysine Motif-Receptor-Like Kinase Gene Family Includes NFP and New Nodule-Expressed Genes". Plant Physiology. 142 (1): 265–279. doi:10.1104/pp.106.084657. ISSN 0032-0889. PMC 1557615. PMID 16844829.
^Buist G, Steen A, Kok J, Kuipers OP (May 2008). "LysM, a widely distributed protein motif for binding to (peptido)glycans". Molecular Microbiology. 68 (4): 838–47. doi:10.1111/j.1365-2958.2008.06211.x. PMID 18430080.
^Bateman A, Bycroft M (June 2000). "The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD)". Journal of Molecular Biology. 299 (4): 1113–9. doi:10.1006/jmbi.2000.3778. PMID 10843862.
molecular biology the LysMdomain is a protein domain found in a wide variety of extracellular proteins and receptors. The LysMdomain is named after the...
specific class of receptor kinases that have LysMdomains in their extracellular domains. The two LysM (lysin motif) receptor kinases (NFR1 and NFR5)...
LysM and putative peptidoglycan-binding domain-containing protein 3 is a protein that in humans is encoded by the LYSMD3 gene. This protein contains a...
being upstream of 'lysM' genes, which encode lysin protein domains, a conserved domain that participates in cell wall degradation. lysM motif RNAs likely...
the methylated Arg/Lys residue and the aromatic residues of the Tudor domain's aromatic-binding cage. Depending on the Tudor domain, this interaction can...
Tuftsin is a tetrapeptide (Thr-Lys-Pro-Arg, TKPR) located in the Fc-domain of the heavy chain of immunoglobulin G (residues 289-292). It has an immunostimulatory...
In molecular biology, the type IV collagen C4 domain (or collagen IV NC1 domain) is a duplicated domain present at the C-terminus of type IV collagens...
where x cannot be a Lys or Arg residue). A negatively charged region frequently follows carboxy-terminal to the pRb-binding domain. {Asp/Asn/Thr} – Leu...
have a three or four-domain organization, with immunoglobulin-like domains surrounding the central catalytic domain. The core domain belongs to the papain-like...
SnoopTag/SnoopCatcher forms an isopeptide bond between a Lys-Asn instead of Lys-Asp found in SpyTag/SpyCatcher. The same domain from RrgA has now been split in a different...
would register a salty, umami taste at 1.22 mM, a Gly-Lys-HCl analog registers a sour and sweet taste at 5.48 mM. Thus, the research findings indicated that...
one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine...
number of domain organizations of PylRS is known: pylS itself consists of an N-terminal tRNA-binding domain and a C-terminal synthase domain, but other...
together to form a type of circular solenoid protein domain called the WD40 domain. WD40 domain-containing proteins have 4 to 16 repeating units, all...
VI and I at Internet Archive Works by James VI and I at LibriVox (public domain audiobooks) Documents on James I curated by The National Archives (United...
Hommes forts (1850) Histoire de la loterie du lingot d'or (1851) Diane de Lys (1851) Le Régent Mustel (1852) Contes et Nouvelles (1853) La Dame aux perles...
additional RNA binding domains and editing domains that cleave incorrectly paired aminoacyl-tRNA molecules. The catalytic domains of all the aaRSs of a...
sidechains of lysine and glutamine is as follows: Gln−(C=O)NH2 + Lys-NH3+ → Gln−(C=O)NH−Lys + NH4+ The ε-amino group of lysine can also react with the α-carboxyl...
bonds in the catalytic domain, and the interactions that strengthen the pocket come from the salt bridges between Asp-45 and Lys-385. With the weaker interactions...
occurs, in which an E2 cysteine residue attacks and replaces the E1. HECT domain type E3 ligases will have one more transthiolation reaction to transfer...
positively charged amino acids (protein sequence positions 282-287), Lys-Asn-Lys-Glu-Lys-Lys, are involved in phospholipid binding (see image on right). β2-GP1...
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