positive regulation of transforming growth factor beta1 production
cartilage development
keratan sulfate catabolic process
response to growth factor
keratan sulfate biosynthetic process
positive regulation of transcription by RNA polymerase II
visual perception
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4060
17022
Ensembl
ENSG00000139329
ENSMUSG00000036446
UniProt
P51884
P51885
RefSeq (mRNA)
NM_002345
NM_008524
RefSeq (protein)
NP_002336
NP_032550
Location (UCSC)
Chr 12: 91.1 – 91.11 Mb
Chr 10: 97.4 – 97.41 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Lumican,[5] also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12.[6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000139329 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000036446 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Blochberger, T. C.; Vergnes, J. P.; Hempel, J.; Hassell, J. R. (1992-01-05). "cDNA to chick lumican (corneal keratan sulfate proteoglycan) reveals homology to the small interstitial proteoglycan gene family and expression in muscle and intestine". The Journal of Biological Chemistry. 267 (1): 347–352. doi:10.1016/S0021-9258(18)48500-6. ISSN 0021-9258. PMID 1370446.
^"Entrez Gene: LUM lumican".
^Chakravarti S, Stallings RL, SundarRaj N, Cornuet PK, Hassell JR (Jun 1995). "Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22". Genomics. 27 (3): 481–8. doi:10.1006/geno.1995.1080. PMID 7558030.
Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Lumican is a proteoglycan...
proteoglycan family" (SLRP). These include decorin, biglycan, fibromodulin and lumican. Proteoglycans are a major component of the animal extracellular matrix...
Gomer, Richard H. (2015-09-22). "TNF-α–stimulated fibroblasts secrete lumican to promote fibrocyte differentiation". Proceedings of the National Academy...
E(E/L)PFPS. Additionally, for three other keratan sulfated proteoglycans, lumican, keratocan, and mimecan (OGN), the consensus sequence NX(T/S) along with...
States Lum, Albania, village in northeastern Albania Lum, Sikkim, India Lumican, a protein encoded by the LUM gene Alfa Lum cycling team IBM LUM (licence...
Global Information
